04-118
Anti-acetyl-Histone H4 (Lys5) Antibody, rabbit monoclonal
culture supernatant, Upstate®
Synonym(s):
H4K5Ac, Histone H4 (acetyl K5)
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
biological source
rabbit
Quality Level
antibody form
culture supernatant
antibody product type
primary antibodies
clone
monoclonal
species reactivity
vertebrates, human
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
acetylation (Lys5)
Gene Information
human ... H4C1(8359)
Specificity
Recognizes Histone H4 when acetylated on Lys5.
Immunogen
Peptide corresponding to Histone H4 containing the sequence [GRG-AcK-GGK] on which Lys5 is acetylated.
Application
Detect acetyl-Histone H4 (Lys5) using this Anti-acetyl-Histone H4 (Lys5) Antibody, rabbit validated for use in WB.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Histones
Histones
Quality
Routinely evaluated by immunoblot.
Target description
11kDa
Physical form
100 μL of rabbit monoclonal IgG cell culture supernatant in 0.1% sodium azide.
Storage and Stability
2 years at -20°C from date of shipment
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
Haipeng Guan et al.
Nature, 620(7974), 669-675 (2023-07-20)
Context-dependent dynamic histone modifications constitute a key epigenetic mechanism in gene regulation1-4. The Rpd3 small (Rpd3S) complex recognizes histone H3 trimethylation on lysine 36 (H3K36me3) and deacetylates histones H3 and H4 at multiple sites across transcribed regions5-7. Here we solved
RSC exploits histone acetylation to abrogate the nucleosomal block to RNA polymerase II elongation.
Carey, Michael, et al.
Molecular Cell, 24, 481-487 (2006)
S Ono et al.
Journal of experimental & clinical cancer research : CR, 21(3), 377-382 (2002-10-19)
Acetylation of core histones is closely linked to transcriptional activation of various genes. The acetylation levels of nucleosomal histones can be modified through a balance of histone acetyltransferases and deacetylases. To elucidate the role of histone acetylation in human gastric
Zengxuan An et al.
The Plant journal : for cell and molecular biology, 103(3), 1010-1024 (2020-04-24)
Histones are highly basic proteins involved in packaging DNA into chromatin, and histone modifications are fundamental in epigenetic regulation in eukaryotes. Among the numerous chromatin modifiers identified in Arabidopsis (Arabidopsis thaliana), MORF-RELATED GENE (MRG)1 and MRG2 have redundant functions in
Epigenetic chromatin modifications in barley after mutagenic treatment.
Braszewska-Zalewska, A; Tylikowska, M; Kwasniewska, J; Szymanowska-Pulka, J
Journal of applied genetics null
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