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03-34-0002

Sigma-Aldrich

H-Arg-Gly-Asp-Ser-OH

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Synonym(s):
H-Arg-Gly-Asp-Ser-OH, Fibronectin Inhibitor, RGDS
Empirical Formula (Hill Notation):
C15H27N7O8
CAS Number:
Molecular Weight:
433.42
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.77

Assay

≥97% (HPLC)

Quality Level

form

powder

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)

color

white to off-white

solubility

water: 1 mg/mL

shipped in

ambient

storage temp.

−20°C

InChI

1S/C15H27N7O8/c16-7(2-1-3-19-15(17)18)12(27)20-5-10(24)21-8(4-11(25)26)13(28)22-9(6-23)14(29)30/h7-9,23H,1-6,16H2,(H,20,27)(H,21,24)(H,22,28)(H,25,26)(H,29,30)(H4,17,18,19)/t7-,8-,9-/m0/s1

InChI key

NNRFRJQMBSBXGO-CIUDSAMLSA-N

General description

Shown to inhibit fibronectin function by binding to platelet-binding sites.

Biochem/physiol Actions

Cell permeable: no
Primary Target
fibronectin
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Standard Handling (A)

Physical form

Supplied as a trifluoroacetate salt.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Perlot, R.L., et al. 2002. J. Bone Miner. Res.17, 66.
Ginsberg, M., et al. 1985. J. Biol. Chem.260, 3931.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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