03-0188-00
SMC® Human Phospho-α-Synuclein (S129) High Sensitivity Immunoassay Kit
Used for ultrasensitive quantification of Human Phospho-α-Synuclein (S129) in human serum, plasma, and cerebrospinal fluid (CSF)
Synonym(s):
p-α-synuclein S129 immunoassay kit, p-α-synuclein Ser129 immunoassay kit, p-α-synuclein Single Molecule Counting Kit, p-α-synuclein ultra-sensitive immunoassay
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About This Item
Product Name
SMC® Human Phospho-α-Synuclein (S129) High Sensitivity Immunoassay Kit, Used for ultrasensitive quantification of Human Phospho-α-Synuclein (S129) in human serum, plasma, and cerebrospinal fluid (CSF)
product line
SMC®
usage
kit sufficient for 96 wells
species reactivity
human
manufacturer/tradename
SMC®
technique(s)
single molecule counting: suitable
input
cerebrospinal fluid (CSF)
serum
plasma (K2 EDTA)
UniProt accession no.
compatibility
for use with FemtoQuest™ and SMCxPRO® instruments
shipped in
wet ice
storage temp.
2-8°C
Packaging
Legal Information
Analysis Note
- Sensitivity: LLOQ 100 fg/mL* (SMCxPRO® Instrument)
- Standard Curve Range: 50-50,000 fg/mL
- Intra-assay CV: <15%
- Inter-assay CV: <20%
- Linearity: Serum: 101% Plasma: 96% CSF: 99%
- Recovery: Serum: 85% Plasma: 89% CSF: 100%
Application
Biochem/physiol Actions
Disclaimer
Features and Benefits
- Femtogram-Scale Analysis: Achieves ultra-low detection limits (fg/mL) in serum, plasma or CSF.
- Advanced Signal Optimization: Incorporates expanded dynamic range with reduced background noise, ensuring reproducibility.
- Seamless Workflow: Combines a familiar sandwich immunoassay architecture with next-generation sensitivity.
- Automation Compatibility: Supports robotic liquid handling integration to reduce touch time and improve efficiency.
- Technical Expertise: Supported by skilled field scientists and technical teams with SMC® expertise.
General description
Phospho-α-synuclein (S129) also contributes to neuroinflammation by activating microglial cells, which can exacerbate neuronal damage and promote disease progression. Its presence in the brain serves as a biomarker for neurodegeneration, highlighting its critical role in the pathophysiology of various neurodegenerative conditions.
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Regulatory Information
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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