03-0185-00
SMC® Human Total Tau High Sensitivity Immunoassay Kit
Used for ultrasensitive quantification of Human Total Tau in human serum, plasma, and cerebrospinal fluid (CSF)
Synonym(s):
Microtubile-associated protein tau immunoassay kit, Neurofibrillary tangle protein immunoassay kit, Tau Single Molecule Counting Kit, Tau ultra-sensitive immunoassay
Select a Size
About This Item
product line
SMC®
usage
kit sufficient for 96 wells
species reactivity
human
manufacturer/tradename
SMC®
input
plasma (K2 EDTA)
cerebrospinal fluid (CSF)
serum
UniProt accession no.
compatibility
for use with FemtoQuest™ and SMCxPRO® instruments
shipped in
wet ice
storage temp.
2-8°C
General description
Elevated tau levels in cerebrospinal fluid (CSF) often indicate ongoing neurodegeneration. Tau also plays a role in neuroinflammation; its presence can activate glial cells, which exacerbate inflammatory responses and promote further neuronal injury. Overall, tau is crucial for maintaining neuronal health, and its dysregulation is central to the pathogenesis of various neurodegenerative disorders.
Application
Biochem/physiol Actions
Features and Benefits
- Highly Sensitive Detection: Accurately measures Total Tau at femtogram/mL concentrations in serum, plasma or CSF.
- Enhanced Dynamic Range: Improved the signal-to-noise ratio with minimized background noise enables dependable assay results.
- Streamlined Workflow: Features a familiar sandwich immunoassay format to simplify adoption by researchers
- Automation Compatible: Designed to work with automated liquid handling systems, decreasing manual intervention and enhancing laboratory efficiency.
- Knowledgeable Technical Support: Supported by skilled field scientists and technical teams with expertise in SMC® assays.
Packaging
Analysis Note
- Sensitivity: LLOQ 4,690 fg/mL* (SMCxPRO® Instrument)
- Standard Curve Range: 1170-1,200,000 fg/mL
- Intra-assay CV: <15%
- Inter-assay CV: <20%
- Linearity: Serum: 107% Plasma: 115% CSF: 103%
- Recovery: Serum 70% Plasma: 82% CSF: 91%
Legal Information
Disclaimer
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B - STOT RE 2 Inhalation
Target Organs
Respiratory Tract
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Regulatory Information
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Related Content
通过适合的免疫检测产品，探索神经免疫和神经炎症细胞因子及神经退行性疾病生物标志物。
在强大的SMCxPRO®检测平台上，采用单分子计数(SMC®)高灵敏度免疫检测试剂盒，准确可靠地检测健康和病患来源的主要神经学蛋白分析物，进行神经科学研究。分析各种神经科学生物标志物，如神经丝蛋白轻链(NF-L)、胶质纤维酸性蛋白(GFAP)、Tau蛋白、β-淀粉样蛋白等。
Discover how to expand neuroscience biomarker research with high sensitivity immunoassays, such as Single Molecule Counting (SMC®) assays. These assays give researchers the tools they need to detect low-abundant blood-based biomarkers and expand biomarker options in neuroscience research.
Explore high-sensitivity SMC® neurology immunoassays that precisely measure low levels of neurology protein analytes, such as NF-L or Tau proteins.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service