03-0184-00
SMC® Human Phospho-Tau (T181) High Sensitivity Immunoassay Kit
Synonym(s):
pTau T181 Single Molecule Counting Kit, pTau T181 immunoassay kit, pTau T181 ultra-sensitive immunoassay, pTau Thr181 immunoassay kit
About This Item
manufacturer/tradename
SMC®
assay range
sensitivity: 0.94 pg/mL
(Lower Limit of Quantification: )
inter-assay cv: ≤12%
intra-assay cv: ≤7%
(five normal plasma samples run in triplicate by 3 different operators on 3 different days.)
technique(s)
single molecule counting: suitable
storage temp.
2-8°C
Related Categories
General description
Assay protocols are similar to existing sandwich ELISA methods with two key differences:
1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification.
2) The Erenna and SMCxPRO® immunoassay systems detect analytes using Single Molecule Counting (SMC®) technology.
Specificity
Specificity was not tested.
Cross Reactivity:
Cross-reactivity was not tested.
Accuracy:
- Minimum of 5 serum samples spiked with average recovery of 97% with a range of 70-138%
- Minimum of 5 plasma samples spiked with average recovery of 97% with a range of 81-127%
- Minimum of 5 CSF samples spiked with average recovery of 108% with a range of 82-146%
Application
This new streamline kit has the following features including:
- Improved options for sample prep and incubation
- Lyophilization of the standard provides the kit at one storage condition
- Removal of a plate transfer step
- Increased reagent volumes to accommodate automation
- Validated to run on both SMCxPRO® and Erenna
Research Category:
- Neuroscience
- Neurological
Research Sub-Category:
- Alzheimer′s Disease
- Aging
- Nervous System
- Neurodegenerative Diseases
- Neurofilament & Neuron Metabolism
- Neuronal & Glial Markers
- Neuroregenerative Medicine
- Neuroscience
Packaging
Components
- Assay Buffer
- pTau T181 Coated Beads
- Standard Diluent
- pTau T181 Detection Antibody
- pTau T181 Standard
- 10X Wash Buffer
- Buffer D
- Elution Buffer B
Legal Information
Disclaimer
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B - STOT RE 2 Inhalation
Target Organs
Respiratory Tract
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Regulatory Information
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Related Content
Neuroscience biomarker research expands with high-sensitivity immunoassays for low-abundant biomarkers.
Explore high-sensitivity SMC® neurology immunoassays that precisely measure low levels of neurology protein analytes, such as NF-L or Tau proteins.
Explore ultrasensitive immunoassay technology with SMC® technology, including its biomarker detection platform, advantages of high sensitivity assays, and more.
Find immunoassays to explore neuroimmunology and neuroinflammation cytokines and neurodegenerative disease biomarkers.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service