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Dulcitol ≥99% (GC)
Sigma-Aldrich
D0256
Dulcitol
Ethylene sulfite 98%
Sigma-Aldrich
G7208
Ethylene sulfite
Galactitol Pharmaceutical Secondary Standard; Certified Reference Material
Supelco
PHR1833
Galactitol
Deoxygalactonojirimycin hydrochloride
Sigma-Aldrich
D9641
Deoxygalactonojirimycin hydrochloride
≥99% (GC)
98%
Pharmaceutical Secondary Standard; Certified Reference Material
G7208-25G
Please contact Customer Service for Availability
CN¥480.79
G7208-25G
Please contact Customer Service for Availability
CN¥480.79
G7208-25G
Please contact Customer Service for Availability
CN¥480.79
G7208-25G
Please contact Customer Service for Availability
CN¥480.79

Description

Synonyms
Dulcite, Galactitol
1,3,2-Dioxathiolan-2-oxide, Cyclic ethylene sulfite, ES, Glycol sulfite
Dulcitol, Dulcite, Galactitol
1,5-Dideoxy-1,5-imino-D-galactitol, Migalastat
CAS Number
Molecular Formula
Empirical Formula (Hill Notation)
: C6H14O6
Empirical Formula (Hill Notation)
: C2H4O3S
Empirical Formula (Hill Notation)
: C6H14O6
Empirical Formula (Hill Notation)
: C6H13NO4 · HCl
Molecular Weight
: 182.17
Molecular Weight
: 108.12
Molecular Weight
: 182.17
Molecular Weight
: 199.63
MDL Number
MFCD00064288
MFCD00005354
MFCD00064288
MFCD00269962
Quality Designations
200
300

Properties

Agency:
Agency:
Agency:
traceable to Ph. Eur. G0049000
traceable to USP 1287711
Agency:
Assay:
≥99% (GC)
Assay:
98%
Assay:
Assay:
≥98% (HPLC)
biological source:
biological source:
biological source:
biological source:
synthetic (organic)
bp:
bp:
159.1 °C (lit.)
bp:
bp:
CofA:
CofA:
CofA:
current certificate can be downloaded
CofA:
color:
white
color:
color:
color:
density:
density:
1.426 g/mL at 25 °C (lit.)
density:
density:
InChI:
1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5+,6-
InChI:
1S/C2H4O3S/c3-6-4-1-2-5-6/h1-2H2
InChI:
1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5+,6-
InChI:
1S/C6H13NO4.ClH/c8-2-3-5(10)6(11)4(9)1-7-3;/h3-11H,1-2H2;1H/t3-,4+,5+,6-;/m1./s1
InChI key:
FBPFZTCFMRRESA-GUCUJZIJSA-N
InChI key:
WDXYVJKNSMILOQ-UHFFFAOYSA-N
InChI key:
FBPFZTCFMRRESA-GUCUJZIJSA-N
InChI key:
ZJIHMALTJRDNQI-OLALXQGDSA-N
application(s):
application(s):
application(s):
pharmaceutical
application(s):
sweetness:
<0.6 × sucrose
sweetness:
sweetness:
sweetness:
packaging:
packaging:
packaging:
pkg of 1 g
packaging:
form:
crystals
form:
liquid
form:
solid
form:
powder or solid
API family:
API family:
API family:
galactose, galactitol
API family:
refractive index:
refractive index:
n20/D 1.445 (lit.)
refractive index:
refractive index:
SMILES string:
OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)CO
SMILES string:
O=S1OCCO1
SMILES string:
OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)CO
SMILES string:
Cl.OC[C@H]1NC[C@H](O)[C@@H](O)[C@H]1O
solubility:
water: 50 mg/mL, clear, colorless
solubility:
solubility:
solubility:
water: soluble 1 mg/mL
grade:
grade:
grade:
certified reference material
pharmaceutical secondary standard
grade:
storage temp.:
storage temp.:
storage temp.:
2-30°C
storage temp.:
−20°C
Quality Level:
Quality Level:
200
Quality Level:
300
Quality Level:

Usage and Safety

Application
Dulcitol (Galactitol), a sugar alcohol derived through reduction of galactose, is important in studies related to cataract formation, hepatosplenomegaly and mental retardation. It is used as a substrate to identify, differentiate and characterize galactitol dehydrogenase(s). Galactitol may be used as a reference compound in analytical procedures developed to analyze sugar alcohols in plants and food.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Deoxygalactonojirimycin hydrochloride has been used as an α-galactosidase A inhibitor to assess the enzymatic activity of α-galactosidase A. It has also been used as an α-galactosidase A inhibitor to study its effects on the mRNA levels in human embryonic kidney (HEK) cells and hippocampal neurons.
Risk and Safety
Storage Class Code:

11 - Combustible Solids

WGK:

WGK 3

Flash Point(F):

Not applicable

Flash Point(C):

Not applicable

Personal Protective Equipment:

Eyeshields, Gloves, type N95 (US)

Storage Class Code:

10 - Combustible liquids

WGK:

WGK 3

Flash Point(F):

197.1 °F

Flash Point(C):

91.7 °C

Personal Protective Equipment:

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Storage Class Code:

11 - Combustible Solids

WGK:

WGK 3

Flash Point(F):

Not applicable

Flash Point(C):

Not applicable

Storage Class Code:

11 - Combustible Solids

WGK:

WGK 3

Personal Protective Equipment:

dust mask type N95 (US), Eyeshields, Gloves