T-074
3,3′,5-Triiodo-L-thyronine (T3) solution
100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®
Synonym(s):
3,3′,5-Triiodo-L-thyronine, O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine, Liothyronine, T3
About This Item
Recommended Products
grade
certified reference material
Quality Level
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
100 μg/mL in methanol with 0.1N NH3
technique(s)
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
mp
234-238 °C (lit.)
application(s)
clinical testing
clinical testing
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This Item | PHR1107 | G8415 | G1251 |
|---|---|---|---|
| technique(s) HPLC: suitable, gas chromatography (GC): suitable | technique(s) HPLC: suitable, gas chromatography (GC): suitable | technique(s) cell culture | mammalian: suitable | technique(s) microbiological culture: suitable |
| application(s) cleaning products | application(s) cleaning products | application(s) pharmaceutical (small molecule) | application(s) - |
| format neat | format neat | format - | format - |
| Quality Level 300 | Quality Level 300 | Quality Level 300 | Quality Level 200 |
| grade certified reference material, TraceCERT® | grade certified reference material, pharmaceutical secondary standard | grade - | grade - |
| manufacturer/tradename Manufactured by: Sigma-Aldrich Production GmbH, Switzerland | manufacturer/tradename - | manufacturer/tradename - | manufacturer/tradename - |
General description
3,3′,5-Triiodo-L-thyronine (T3) is a thyroid hormone and active form of L-thyroxine (T4), formed by deiodinase type I or II. It supports various physiological functions, such as oxygen consumption, carbohydrate metabolism, protein synthesis, and neural development. Free and total T3 serum levels are measured by LC-MS/MS for the determination of hyperthyroidism caused by excess T3.
Application
- Multi-residue determination of seven thyroid hormones in placenta samples by isotope dilution liquid chromatography-quadrupole time-of-flight mass spectrometry (LC-Q-TOF-MS)
- Parts-per-trillion analysis of five thyroid hormones in zebrafish larvae by their solid phase extraction (SPE) and ultra-high performance liquid chromatography-electrospray ionization- tandem mass spectrometric (UPLC-ESI/MS/MS) analysis
- Simultaneous analysis of six free thyroid hormones in bovine serum samples by ultrafiltration and high-performance liquid chromatography (HPLC)-tandem mass spectrometry (MS/MS)
- Determination of six thyroid hormones in mouse tissue samples by isotope dilution nano-ultraperformance liquid chromatography–quadrupole time-of-flight mass spectrometry (Q-TOF-MS)
- Identification and quantification of triiodothyronine and thyroxine in rat serum samples using liquid chromatography-tandem mass spectrometry (LC-MS/MS)
Features and Benefits
- Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
- Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
- Rigorously tested through real-time stability studies to ensure accuracy and shelf life
- Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
- Flame sealed under argon into ampoules for long-term shelf life
- Offered in a convenient, DEA-exempt format to improve laboratory efficiency
Legal Information
related product
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Flam. Liq. 2 - STOT SE 1
Target Organs
Eyes,Central nervous system
Storage Class Code
3 - Flammable liquids
WGK
WGK 2
Flash Point(F)
49.5 °F - closed cup
Flash Point(C)
9.7 °C - closed cup
Regulatory Information
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Certificates of Analysis (COA)
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Articles
Determination of free thyroid hormones (T3 & T4) in serum by LC-MS/MS following a streamlined 1-hour BioSPME sample preparation.
Protocols
Determination of the thyroid hormones T4, T3 and rT3 from plasma using an Ascentis Express RP-Amide cartridge to trap the analytes, and a Phenyl-Hexyl column to resolve them.
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