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S-106

Supelco

JWH-018 5-Pentanoic acid beta-D-glucuronide solution

100 μg/mL (Acetonitrile:Water (90:10) (v/v)), certified reference material, ampule of 1 mL

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Empirical Formula (Hill Notation):
C30H29NO9
CAS Number:
Molecular Weight:
547.55
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Quality Level

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL (Acetonitrile:Water (90:10) (v/v))

application(s)

forensics and toxicology
forensics and toxicology

format

single component solution

storage temp.

−70°C

General description

The glucuronide metabolite of a secondary urinary metabolite of JWH-018, a synthetic cannabinoid found in several versions of the herbal mixture "Spice". Illicit use of this Spice cannabinoid centers on its psychoactive effects which mimic those of Δ9-THC in cannabis. This certified Snap-N-Spike® solution is suitable as starting material for calibrators and controls in Spice cannabinoid testing methods by GC/MS or LC/MS for urine drug testing, forensic analysis, and clinical toxicology applications.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

WGK

WGK 2

Flash Point(F)

35.6 °F

Flash Point(C)

2.0 °C

Regulatory Information

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Certificates of Analysis (COA)

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Ping Liu et al.
Nature communications, 4, 1911-1911 (2013-05-30)
Nematode neurons generally produce graded potentials instead of action potentials. It is unclear how the graded potentials control postsynaptic cells under physiological conditions. Here we show that postsynaptic currents frequently occur in bursts at the neuromuscular junction of Caenorhabditis elegans.
Michael B Manookin et al.
Neuron, 97(6), 1327-1340 (2018-03-06)
Considerable theoretical and experimental effort has been dedicated to understanding how neural circuits detect visual motion. In primates, much is known about the cortical circuits that contribute to motion processing, but the role of the retina in this fundamental neural
C Alex Goddard et al.
Journal of neurophysiology, 98(6), 3486-3493 (2007-09-28)
Cholinergic neurons in the parabigeminal nucleus of the rat midbrain were studied in an acute slice preparation. Spontaneous, regular action potentials were observed both with cell-attached patch recordings as well as with whole cell current-clamp recordings. The spontaneous activity of
Zoé Christenson Wick et al.
eLife, 8 (2019-10-15)
The hippocampus, a brain region that is important for spatial navigation and episodic memory, benefits from a rich diversity of neuronal cell-types. Through the use of an intersectional genetic viral vector approach in mice, we report novel hippocampal neurons which
Henrik Ring et al.
PloS one, 7(5), e36874-e36874 (2012-05-17)
GABA is more than the main inhibitory neurotransmitter found in the adult CNS. Several studies have shown that GABA regulates the proliferation of progenitor and stem cells. This work examined the effects of the GABA(A) receptor system on the proliferation

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