Skip to Content
Merck
CN
All Photos(1)

Documents

Safety Information

S-033

Supelco

JWH-018 5-Pentanoic acid metabolite solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Synonym(s):

JWH-018 5-Pentanoic acid

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C24H21NO3
Molecular Weight:
371.43
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology
forensics and toxicology

format

single component solution

storage temp.

−20°C

SMILES string

O=C(C1=CC=CC2=C1C=CC=C2)C3=CN(CCCCC(O)=O)C4=C3C=CC=C4

InChI

1S/C24H21NO3/c26-23(27)14-5-6-15-25-16-21(19-11-3-4-13-22(19)25)24(28)20-12-7-9-17-8-1-2-10-18(17)20/h1-4,7-13,16H,5-6,14-15H2,(H,26,27)

InChI key

BYIVGHIYNFQIJX-UHFFFAOYSA-N

General description

A secondary urinary metabolite of JWH-018, a synthetic cannabinoid found in many blends of the herbal mixture Spice also known as K2, Genie, or Demon. Our certified Spice cannabinoid solution standards are DEA-exempt allowing laboratories to order these standards without DEA paperwork.

Application


  • Advanced Mass Spectrometry Techniques: JWH-018 has been utilized in pioneering mass spectrometry research to enhance the detection and analysis of synthetic cannabinoids through radial electric field-driven collision-induced dissociation. This technique represents a significant advancement in forensic toxicology and pharmacology, enabling precise identification and quantification of complex substances (Ruan et al., 2023).

  • Leukemia and Stem Cell Research: JWH-018 is studied for its potential therapeutic effects on leukemia and leukemic stem cells, offering a novel approach to cancer treatment. This research explores how synthetic cannabinoids can influence cancer pathogenesis and highlights possible applications in developing new cancer therapies (Salcin et al., 2024).

  • Yeast Biosensor Development: Research on JWH-018 has contributed to the development of a yeast biosensor capable of cannabinoid detection. This biosensor is designed for biomedical and biotechnological applications, including point-of-use cannabinoid determination, demonstrating the versatility of JWH-018 in receptor research and drug testing (Miettinen et al., 2022).

  • Comparative Pharmacology Studies: JWH-018 has been used in comparative studies of molecular signaling between synthetic cannabinoids and TRPV1 channel activation. These studies are crucial for understanding the pharmacological differences between various cannabinoids and their effects on the human body, providing insights into potential therapeutic uses and side effects (Andersen and Walsh, 2021).

  • Drug Analysis in Blood Plasma: JWH-018 has also been part of research focused on enhancing drug analysis techniques in blood plasma. By developing non-fouling, sensitive surface-enhanced Raman scattering (SERS) substrates, researchers aim to improve the detection of potent drugs, including JWH-018, directly in complex biological matrices, which is essential for clinical diagnostics and forensic investigations (Masterson et al., 2021).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

WGK

WGK 1

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Regulatory Information

危险化学品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service