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Merck
CN

S-018

Sufentanil-D5 solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C22D5H25N2O2S
CAS Number:
1884682-16-9
Molecular Weight:
391.58
NACRES:
NA.24
UNSPSC Code:
41116107
EC Number:
200-659-6

Key Documents

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Product Name

Sufentanil-D5 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

form

liquid

InChI key

GGCSSNBKKAUURC-SMZGMGDZSA-N

InChI

1S/C22H30N2O2S/c1-3-21(25)24(19-8-5-4-6-9-19)22(18-26-2)12-15-23(16-13-22)14-11-20-10-7-17-27-20/h4-10,17H,3,11-16,18H2,1-2H3/i3D2

SMILES string

[2H]C([2H])(C)C(=O)N(c1ccccc1)C2(CCN(CCc3cccs3)CC2)COC

grade

certified reference material

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

concentration

100 μg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

2-8°C

Quality Level

300

Related Categories

General description

Sufentanil is a short acting synthetic opioid analgesic used as a painkiller during medical operations. This stable-labeled internal standard is suitable for quantitation of sufentanil levels in urine, serum, or plasma by LC/MS or GC/MS for clinical toxicology, pain prescription monitoring, forensic analysis, or isotope dilution methods. Sufentanil is sold under the trade name Sufenta.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Regulatory Information

监管及禁止进口产品
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Certificates of Analysis (COA)

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Harold S Minkowitz et al.
Regional anesthesia and pain medicine, 38(2), 131-139 (2012-12-29)
A sublingual sufentanil tablet is being developed as a potential alternative to intravenous (IV) opioids for the management of postoperative pain. The objective of these studies was to evaluate the pharmacokinetics, efficacy, and safety of sublingual sufentanil tablets for postoperative
C Jeleazcov et al.
British journal of anaesthesia, 109(5), 698-706 (2012-07-27)
Target controlled infusion (TCI) with sufentanil is usually performed using the Gepts model, which was derived from patients undergoing general surgery. It is, however, known that pharmacokinetics of sufentanil can be changed during cardiopulmonary bypass (CPB). We tested whether TCI
Q L Chen et al.
Acta anaesthesiologica Scandinavica, 57(2), 236-242 (2012-08-14)
Sufentanil is widely used in clinical anaesthesia because of its protective effects against ischaemia/reperfusion injury. Diabetes mellitus elevates the activity of glycogen synthase kinase-3β (GSK-3β), thereby increasing the permeability of mitochondrial transition pore. This study investigated the role of GSK-3β
Sébastien Grastilleur et al.
Biological chemistry, 394(3), 361-368 (2013-01-18)
Postoperative pain management is a clinical challenge that can be complicated by opioid-induced hyperalgesia (OIH). Kinin receptors could mediate both the acute and chronic phases of inflammation and pain. A few recent studies suggest that dynorphin A could maintain neuropathic
S Dango et al.
British journal of anaesthesia, 110(3), 443-449 (2012-11-16)
Although thoracic epidural analgesia (TEA) is considered the gold standard for post-thoracotomy pain relief, thoracic paravertebral block (PVB) and intrathecal opioid (ITO) administration have also been shown to be efficacious. We hypothesized that the combination of PVB and ITO provides
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