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O-904

Supelco

Oxazepam-d5 solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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Empirical Formula (Hill Notation):
C15D5H6ClN2O2
CAS Number:
65854-78-6
Molecular Weight:
291.74
EC Number:
200-659-6
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

shipped in

wet ice

storage temp.

−20°C

SMILES string

[2H]c1c([2H])c([2H])c(c([2H])c1[2H])C2=NC(O)C(=O)Nc3ccc(Cl)cc23

InChI

1S/C15H11ClN2O2/c16-10-6-7-12-11(8-10)13(9-4-2-1-3-5-9)18-15(20)14(19)17-12/h1-8,15,20H,(H,17,19)/i1D,2D,3D,4D,5D

InChI key

ADIMAYPTOBDMTL-RALIUCGRSA-N

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General description

Oxazepam is a benzodiazepine drug used to treat anxiety and insomnia and to control the symptoms of alcohol withdrawal. This stable-labeled internal standard is suitable for isotope dilution methods or the quantitation of oxazepam levels using GC/MS or LC/MS in testing applications such as clinical toxicology, urine drug testing, forensic analysis or pain prescription monitoring.

Application


  • Oxazepam-d5 as an internal standard in toxicology: Oxazepam-d5 is utilized in gas chromatography-tandem mass spectrometry for the determination of lorazepam and its metabolites in plasma and urine, demonstrating its utility as a stable isotope-labeled compound for enhancing analytical specificity and accuracy (Pichini et al., 1999).

  • Stable isotope-labeled Oxazepam for quantification in forensic science: This compound serves as a critical internal standard in sensitive GC-MS procedures for analyzing benzodiazepines and their metabolites in biological specimens, vital for forensic applications (elSohly et al., 1997).

  • Deuterated Oxazepam reference material for mass spectrometry: Oxazepam-d5 is used in the development of analytical methods for the detection of benzodiazepine metabolites, providing high accuracy and precision essential for clinical and toxicological evaluations (Meatherall, 1994).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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O-902

Oxazepam solution, 1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

B-033

Benzodiazepine Multi-component Mixture-8 solution, 250 μg/mL each component in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

IMF-020S

iMethod Test Kit for Benzodiazepines with Synthetic Urine, kit of 23 × 1.0 mL ampules, certified reference material, Cerilliant®

O-023

Oxazepam glucuronide solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

O-901

Oxazepam-d5 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

O-057

Oxazepam glucuronide lithium salt solution, 100 μg/mL in methanol ((as free carboxylate)), certified reference material, ampule of 1 mL, Cerilliant®

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

WGK

WGK 1

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Bernhard Watzer et al.
International journal of legal medicine, 129(4), 759-769 (2014-12-20)
Arthrotec(®) (AT) is a combination of diclofenac, a nonsteroidal anti-inflammatory drug (NSAID), and misoprostol (MP), a synthetic analogue of prostaglandin E1 (PGE1). MP is a lipophilic methyl ester prodrug. It is readily metabolized to the biologically active misoprostol acid (MPA).
Niclas Stephanson et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 985, 189-196 (2015-02-18)
A mass spectrometric method for drugs of abuse testing in exhaled breath employing a sampling device collecting aerosol particles was developed and applied in routine use. Analytes covered were amphetamine, methamphetamine, 6-acetylmorphine, morphine, cocaine, benzoylecgonine, diazepam, oxazepam and tetrahydrocannabinol. The
André Valle de Bairros et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 975, 24-33 (2014-12-03)
In this study, it is shown a method for the determination of benzodiazepines and their main metabolites in urine samples by hollow-fiber liquid-phase microextraction (LPME) in the three-phase mode. Initially, the hydrolysis step was performed using 100 μL of sodium

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