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N-921

Supelco

Norbuprenorphine-D3 solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C25H32D3NO4
CAS Number:
350482-19-8
Molecular Weight:
416.57
MDL number:
MFCD01861544
UNSPSC Code:
41116107
PubChem Substance ID:
329818615
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland)

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

2-8°C

SMILES string

[2H]C([2H])([2H])O[C@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]4Cc5ccc(O)c6O[C@@H]2[C@]3(CCN4)c56

InChI

1S/C25H35NO4/c1-21(2,3)22(4,28)16-13-23-8-9-25(16,29-5)20-24(23)10-11-26-17(23)12-14-6-7-15(27)19(30-20)18(14)24/h6-7,16-17,20,26-28H,8-13H2,1-5H3/t16-,17-,20-,22+,23-,24+,25-/m1/s1/i5D3

InChI key

YOYLLRBMGQRFTN-QLWKBOQPSA-N

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General description

Norbuprenorphine is the primary active metabolite of the opiate buprenorphine in urine. This internal standard is suitable for quantitation of norbuprenorphine levels or isotope dilution methods by GC/MS or LC/MS for pain prescription monitoring, clinical toxicology, urine drug testing or forensic analysis. Buprenorphine, sold under trade names such as Buprenex®, Subutex® and Suboxone®, is an opiate drug used to treat opioid addiction and to moderate acute pain.

Application


  • Improving GC-MS Analysis of Opioids: Norbuprenorphine-D₃ is utilized to enhance the accuracy of gas chromatography-mass spectrometry (GC-MS) determination of norbuprenorphine, particularly when high concentrations of buprenorphine are present in urine samples. This method is vital for opioid research and bioanalysis, ensuring reliable quantification of buprenorphine metabolites in clinical and forensic settings (Gervais and Hobbs, 2016).

Legal Information

Buprenex is a registered trademark of Reckitt & Colman (Overseas) Ltd
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Suboxone is a registered trademark of RB Pharmaceuticals Limited
Subutex is a registered trademark of RB Pharmaceuticals Limited

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Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

WGK

WGK 1

Flash Point(F)

49.5 °F

Flash Point(C)

9.7 °C

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

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