N-046
(+)-Norpseudoephedrine hydrochloride solution
100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
Synonym(s):
Cathine hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C9H14ClNO
CAS Number:
Molecular Weight:
187.67
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
grade
certified reference material
Quality Level
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
drug control
Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)
concentration
100 μg/mL in methanol (as free base)
technique(s)
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
application(s)
forensics and toxicology
format
single component solution
storage temp.
−20°C
SMILES string
Cl.C[C@H](N)[C@@H](O)c1ccccc1
InChI
1S/C9H13NO.ClH/c1-7(10)9(11)8-5-3-2-4-6-8;/h2-7,9,11H,10H2,1H3;1H/t7-,9+;/m0./s1
InChI key
DYWNLSQWJMTVGJ-DKXTVVGFSA-N
General description
A certified reference solution suitable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications, from clinical toxicology and forensic analysis to urine drug testing and sports testing. (+)-Norpseudoephedrine, also known as cathine, is a psychoactive stimulant of the phenethylamine and amphetamine classes.
Application
- Phytochemical Profiling and Therapeutic Activities: (+)-Norpseudoephedrine hydrochloride solution is utilized in phytochemical profiling studies, specifically analyzing the toxicity, wound healing, analgesic, and anti-inflammatory properties of Musa paradisiaca L. stem extracts. This research enhances the understanding of natural products in pharmaceutical applications, particularly for their therapeutic potential (Ekweogu et al., 2024).
- Chiral Analysis of Stimulant Drugs: The solution is critical in the development and application of a chiral high-performance liquid chromatography-tandem mass spectrometry method for forensic analysis. This method is used to determine the presence of related amphetamine-type stimulants, providing essential data for law enforcement and drug regulation agencies (Schwelm et al., 2020).
- Microbial Production of Phenylalkylamines: (+)-Norpseudoephedrine hydrochloride serves as a biochemical tool in studies focused on the microbial production of ephedrine and pseudoephedrine, revealing significant implications for the manufacturing of pharmaceuticals and enhancing our understanding of metabolic pathways (Morris et al., 2018).
- Improved Detection Methods for Cathinones: This compound is integral to the improved gas chromatography method for detecting active principles in Catha edulis, demonstrating its utility in identifying and quantifying natural sources of cathinones, which are important for both medical research and drug enforcement (Dell′acqua et al., 2013).
- Chiral Capillary Electrophoresis: Used in chiral capillary electrophoresis for methamphetamine profiling, (+)-Norpseudoephedrine hydrochloride solution assists in distinguishing isomers in forensic samples, which is critical for the precise identification of controlled substances in forensic settings (Iwata et al., 2013).
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
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Description
Pricing
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
WGK
WGK 2
Flash Point(F)
closed cup
Flash Point(C)
closed cup
Regulatory Information
监管及禁止进口产品
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Kuei Hui Chan et al.
Journal of analytical toxicology, 33(3), 162-166 (2009-04-18)
Sho-seiryu-to is one of the most common Traditional Chinese Medicine preparations for the attenuation of colds. Ephedrae Herba is one of the prescriptions of Sho-seiryu-to. The major ingredients of Ephedrae Herba, ephedrines, are banned substances on the World Anti-Doping Agency
Raz Krizevski et al.
Journal of ethnopharmacology, 114(3), 432-438 (2007-10-12)
Khat (Catha edulis Forsk., Celastraceae) is a perennial shrub that was introduced to Israel by Yemenite immigrants. Khat young leaves are chewed as a stimulant. The main stimulating active principles in this plant are the phenylpropylamino alkaloids (-)-cathinone [(S)-alpha-aminopropiophenone], (+)-cathine
Carlos Castillo-Henkel et al.
Proceedings of the Western Pharmacology Society, 53, 33-36 (2010-01-01)
Here we contrast the vascular smooth muscle contractility produced by D-nor-pseudoephedrine, alone or combined with triiodothyronine, on the aorta and coronary vasculature of the rat. At high concentrations (greater than those found in normal therapeutic dosing) D-nor-pseudoephedrine contracted the aorta.
John S Chappell et al.
Forensic science international, 195(1-3), 108-120 (2009-12-29)
A primary concern with the forensic analysis of the khat plant (Catha edulis) has been the need to preserve the principle psychoactive component, cathinone, which converts to the less-active substance, cathine, after harvesting. The loss of cathinone has serious legal
Hyeon-Kyu Lee et al.
The Journal of organic chemistry, 77(12), 5454-5460 (2012-05-25)
Each of the enantiomers of both norephedrine and norpseudoephedrine were stereoselectively prepared from the common, prochiral cyclic sulfamidate imine of racemic 1-hydroxy-1-phenyl-propan-2-one by employing asymmetric transfer hydrogenation (ATH) catalyzed by the well-defined chiral Rh-complexes, (S,S)- or (R,R)-Cp*RhCl(TsDPEN), and HCO(2)H/Et(3)N as
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