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L-907

Supelco

Lormetazepam solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C16H12Cl2N2O2
CAS Number:
Molecular Weight:
335.18
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

CN1C(=O)C(O)N=C(c2ccccc2Cl)c3cc(Cl)ccc13

InChI

1S/C16H12Cl2N2O2/c1-20-13-7-6-9(17)8-11(13)14(19-15(21)16(20)22)10-4-2-3-5-12(10)18/h2-8,15,21H,1H3

InChI key

FJIKWRGCXUCUIG-UHFFFAOYSA-N

General description

Lormetazepam is a benzodiazepine with sedative-hypnotic, anxiolytic, anticonvulsant, and muscle relaxant effects. This certified solution standard is suitable for use in LC/MS or GC/MS applications for urine drug testing, clinical toxicology, and forensic analysis. Lormetazepam is sold under trade names Loramet and Noctamid for treatment of insomnia.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

WGK

WGK 1

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Kazuaki Shinomiya et al.
European journal of pharmacology, 460(2-3), 139-144 (2003-02-01)
The present study was performed to develop a new sleep disturbance model for evaluating hypnotic potencies by placing rats on a grid suspended over water up to 1 cm under the grid surface. When rats were placed on the grid
Luc Staner et al.
Psychopharmacology, 181(4), 790-798 (2005-07-19)
Most studies that investigated the next-day residual effects of hypnotic drugs on daytime driving performances were performed on healthy subjects and after a single drug administration. In the present study, we further examine whether the results of these studies could
[Paroxetine-induced severe hyponatremic rhabdomyolisis].
M Portilla-Botelho et al.
Medicina intensiva, 32(7), 365-366 (2008-10-10)
D Riemann et al.
Pharmacopsychiatry, 35(5), 165-174 (2002-09-19)
In recent years, sedating antidepressants have been increasingly used to treat primary insomnia. Up to now, only one open pilot study with trimipramine and one double-blind placebo-controlled study with doxepin have provided scientific support for this approach in treating primary
W Dimpfel et al.
European journal of medical research, 3(10), 453-460 (1998-10-01)
Sleep in humans is classically assessed by recording a multichannel electroencephalogram (EEG) in connection with an electrooculogram (EOG) and an electromyogram (EMG). In general, human sleep is manually staged into 6 categories (from awake through REM sleep to stage 4

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