I-034
Human Insulin solution
100 μg/mL in PBS, pH 7.2, certified reference material, ampule of 100 μL, Cerilliant®
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About This Item
Empirical Formula (Hill Notation):
C257H383N65O77S6
CAS Number:
Molecular Weight:
5807.57
UNSPSC Code:
41116107
NACRES:
NA.24
InChI key
PBGKTOXHQIOBKM-FHFVDXKLSA-N
grade
certified reference material
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 100 μL
manufacturer/tradename
Cerilliant®
concentration
100 μg/mL in PBS, pH 7.2
technique(s)
liquid chromatography (LC): suitable
application(s)
clinical testing
format
single component solution
storage temp.
−20°C
General description
Human insulin is a peptide hormone, composed of 51 amino acids, produced by beta cells of the pancreatic islets. Insulin regulates the metabolism of carbohydrates, fats and protein by promoting the absorption of, especially glucose from the blood into liver, fat and skeletal muscle cells. Insulin levels are routinely measured to evaluate insulin production; diagnose insulin-producing tumors; determine hypoglycemia or to identify insulin resistance. This certified Snap-N-Spike® solution of the fully-intact human insulin protein is suitable for use as starting material in calibrators and controls in LC-MS/MS insulin testing methods.
The Recombinant Human Insulin in phosphate buffered saline (PBS), pH 7.2 (solution) is a standard that fulfills the criteria set by ISO for a certified reference material and a primary standard. It is traceable to the SI and higher order standards through a continuous series of comparisons.
Application
Human Insulin solution is suitable for the in vitro identification, calibration, and quantification of the analyte(s) in analytical and R&D applications.
Features and Benefits
- The active insulin content is determined through quantitative amino acid analysis (AAA) and chromatographic purity.
- Each raw material used in the standard has undergone identification and thorough characterization using multiple analytical techniques.
- A Mass Balance Purity Factor is assigned to each raw material.
- The standard is prepared using balances that are fully qualified and calibrated to meet ISO 17025 requirements.
- The standard is prepared and certified under the ISO 17034, ISO/IEC 17025, ISO 9001, and ISO 13485 standards.
Preparation Note
- Thaw the product at refrigerator or room temperature.
- Mix well before use.
- Once thawed, do not refreeze the product.
- Use established good laboratory practices to quantitatively transfer the desired volume and spike the product into a matrix or dilute it to the desired concentration.
Other Notes
This product′s purpose is for testing. THIS PRODUCT IS NOT INTENDED FOR HUMAN OR THERAPEUTIC USE. Please refer to the safety data sheet for specific details regarding any possible hazards and necessary precautions.
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
监管及禁止进口产品
This item has
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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