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D-101

Supelco

(±)-2,5-Dimethoxy-4-bromoamphetamine hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

Synonym(s):

DL-DOB hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C11H16BrNO2 · HCl
CAS Number:
29705-96-2
Molecular Weight:
310.62
EC Number:
200-659-6
MDL number:
MFCD11975207
UNSPSC Code:
41116107
PubChem Substance ID:
329798659

grade

certified reference material

form

liquid

feature

(Snap-N-Spike®)

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)

concentration

1.0 mg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

pharmaceutical (small molecule)

format

single component solution

storage temp.

−20°C

SMILES string

NC(C)CC1=CC(OC)=C(Br)C=C1OC.Cl

InChI

1S/C11H16BrNO2.ClH/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2;/h5-7H,4,13H2,1-3H3;1H

InChI key

SPBBKPOIDQIWDZ-UHFFFAOYSA-N

General description

Also known as bromo-DMA or brolamfetamine, DOB is a D-substituted amphetamine of the phenethylamine family of psychedelics. This designer drug, often misrepresented as LSD, is an extremely potent hallucinogen with a long duration of action of up to several days. This certified Snap-N-Spike® solution is suitable for use as starting material in calibrators or controls for phenethylamine testing methods by LC/MS or GC/MS for clinical toxicology, forensic analysis, or urine drug testing applications.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Regulatory Information

监管及禁止进口产品

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Michael A Benneyworth et al.
Molecular pharmacology, 72(2), 477-484 (2007-05-29)
Recent clinical studies reveal that selective agonists of group II metabotropic glutamate (mGlu) receptors have robust efficacy in treating positive and negative symptoms in patients with schizophrenia. Group II mGlu receptor agonists also modulate the in vivo activity of psychotomimetic
H Nishio et al.
General pharmacology, 33(1), 51-57 (1999-07-31)
We detected specific binding of 3H-ketanserin (0.6 nM) in rat renal cortical membrane preparations (4.70 +/- 0.57 fmol/mg protein) and mesangial cells (7.55 +/- 0.92 fmole/10(6) cells). Thus, the value in the renal cortical membrane corresponded to 15% of that
Helena Carmo et al.
Toxicology, 206(1), 75-89 (2004-12-14)
4-Bromo-2,5-dimethoxyphenethylamine (2C-B) is a psychoactive designer drug of abuse that is sold under the street names "Venus", "Bromo", "Erox", "XTC" or "Nexus". Concern has been raised because only little is known about its toxicity and metabolism in humans. In the
M E Bronson et al.
Pharmacology, biochemistry, and behavior, 51(2-3), 473-475 (1995-06-01)
The effects of 4-bromo-2,5-dimethoxyphenethylamine (Nexus), 3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxyphenyl-2-butanamine (BDB), and cathinone were studied in the newly hatched chicken and compared to the effects of d-amphetamine and three hallucinogens in the same species. Cathinone, a psychomotor stimulant in man (6), produced
Pablo R Moya et al.
The Journal of pharmacology and experimental therapeutics, 321(3), 1054-1061 (2007-03-06)
2,5-Dimethoxy-4-substituted phenylisopropylamines and phenethylamines are 5-hydroxytryptamine (serotonin) (5-HT)(2A/2C) agonists. The former are partial to full agonists, whereas the latter are partial to weak agonists. However, most data come from studies analyzing phospholipase C (PLC)-mediated responses, although additional effectors [e.g., phospholipase
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