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D-069

Supelco

Desmethylolanzapine dihydrochloride solution

1.0 mg/mL in acetonitrile: water (1:1) (as free base), ampule of 1 mL, certified reference material, Cerilliant®

Synonym(s):

Desmethylolanzapine dihydrochloride solution

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About This Item

Empirical Formula (Hill Notation):
C16H18N4S · H2Cl2
CAS Number:
161696-76-0
Molecular Weight:
371.33
MDL number:
MFCD29917817
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in acetonitrile: water (1:1) (as free base)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

CC1=CC2=C(S1)NC3=C(C=CC=C3)N=C2N4CCNCC4.[H]Cl.[H]Cl

InChI

1S/C16H18N4S/c1-11-10-12-15(20-8-6-17-7-9-20)18-13-4-2-3-5-14(13)19-16(12)21-11/h2-5,10,17,19H,6-9H2,1H3

InChI key

FHPIXVHJEIZKJW-UHFFFAOYSA-N

Related Categories

General description

Desmethylolanzapine is the primary metabolite of olanzapine, marketed as the atypical antipsychotic Zyprexa®for the treatment of schizophrenia and bipolar disorder. This new certified solution standard is suitable for use in LC or GC applications including clinical toxicology analysis, forensic testing, or therapeutic drug monitoring.

Application

  • Desmethylolanzapine Dihydrochloride Solution: This specialized solution is pivotal in neuropharmacology research, primarily used to study the pharmacokinetics and metabolic pathways of olanzapine, a prominent antipsychotic medication used in the treatment of schizophrenia and bipolar disorder.
  • Olanzapine Metabolite Research: As an active metabolite of olanzapine, desmethylolanzapine dihydrochloride provides critical insights in antipsychotic drug studies, helping to understand the drug′s efficacy, side effects, and metabolism.
  • Antipsychotic Drug Studies: This solution is used extensively in biochemical assays to evaluate the interaction of olanzapine metabolites with various neurotransmitter systems, aiding in the development of more effective and safer antipsychotic treatments.
  • Biochemical Assay Reagents: Desmethylolanzapine dihydrochloride serves as a reagent in various biochemical assays, facilitating research into the molecular mechanisms of psychiatric disorders and the therapeutic potential of benzodiazepines.
  • Neuropharmacology Research Chemicals: This compound is a key research chemical in neuropharmacological studies, used to simulate and study the effects of long-term antipsychotic medication usage on the brain and body.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Zyprexa is a registered trademark of Eli Lilly and Co.

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Statements

H225,H302,H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

WGK

WGK 2

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Regulatory Information

危险化学品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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