Skip to Content
Merck
CN
All Photos(1)

Documents

Safety Information

D-015

Supelco

Diphenhydramine hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

Sign Into View Organizational & Contract Pricing
All Photos(1)
Empirical Formula (Hill Notation):
C17H22ClNO
CAS Number:
147-24-0
Molecular Weight:
291.82
EC Number:
200-659-6
MDL number:
MFCD00012479
UNSPSC Code:
41116107
PubChem Substance ID:
329798588
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

pharmaceutical (small molecule)

format

single component solution

storage temp.

−20°C

SMILES string

CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2.Cl

InChI

1S/C17H21NO.ClH/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;/h3-12,17H,13-14H2,1-2H3;1H

InChI key

PCHPORCSPXIHLZ-UHFFFAOYSA-N

Gene Information

human ... HRH1(3269)

Related Categories

General description

Diphenhydramine is an antihistamine sold over the counter under the trade name Benadryl® and in other over the counter medications such as Tylenol PM, Advil PM, and Excedrin PM. Dihydramine is also consumed recreationally as a euphoriant and a deliriant.

Application


  • Hepatoprotective effects of polyphenols: Studies on the hepatoprotective effects of polyphenol-enriched fractions against oxidative stress in Acetaminophen-induced liver injury incorporate the analysis of Acetaminophen Related Compound D. This research underscores its relevance in pharmacology and toxicology, providing a deeper understanding of drug-induced liver injuries and potential therapeutic approaches (Wu et al., 2017).


Legal Information

Benadryl is a registered trademark of Johnson & Johnson
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes,Central nervous system

WGK

WGK 2

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Regulatory Information

危险化学品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Don W Coulter et al.
Anti-cancer drugs, 24(4), 415-421 (2013-01-19)
A pediatric study has established a maximum tolerated dose (MTD) for temsirolimus (Tem) of more than 150 mg/m intravenously/week. A phase I trial was conducted to establish the MTD for Tem in combination with valproic acid (VPA) in children and
Marc Marino et al.
Journal of neuroscience methods, 211(1), 1-10 (2012-09-14)
Pruritus, the sensation of itch, which evokes reflex scratching behavior, has a diverse etiology. Because of its clinical significance, mechanisms of pruriception are an important topic. In the present work we describe and validate a paw motion detector (PMD) system.
Edward Topp et al.
The Science of the total environment, 439, 136-140 (2012-10-16)
The widely used antihistamine diphenhydramine is present in municipal biosolids, and is detected in runoff from agricultural land fertilized with biosolids. In the present study the kinetics and major pathways of diphenhydramine dissipation in a loam, sandy loam, and clay
Eugene W Schwilke et al.
Journal of forensic sciences, 51(5), 1191-1198 (2006-10-05)
We have previously reported on patterns of drug and alcohol use in fatally injured drivers in Washington State. Here we revisit that population to examine how drug use patterns have changed in the intervening 9 years. Blood and serum specimens
A D Rollstin et al.
Clinical toxicology (Philadelphia, Pa.), 51(1), 50-53 (2012-12-01)
There are few reports of acetaminophen overdose in hypothermic patients and even fewer reports describing profound hypothermia. The kinetics, risk of hepatotoxicity, and the possible dose adjustments to N-acetylcysteine (NAC) therapy are not known in this setting. A 37-year-old female
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service