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A-027

Supelco

6-Acetylmorphine-d6 solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C19D6H15NO4
CAS Number:
Molecular Weight:
333.41
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

SNAP-N-SPIKE®. SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

concentration

1.0 mg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

SMILES string

[2H]C([2H])([2H])N1CC[C@]23C4Oc5c(O)ccc(CC1C2C=C[C@@H]4OC(=O)C([2H])([2H])[2H])c35

InChI

1S/C19H21NO4/c1-10(21)23-15-6-4-12-13-9-11-3-5-14(22)17-16(11)19(12,18(15)24-17)7-8-20(13)2/h3-6,12-13,15,18,22H,7-9H2,1-2H3/t12-,13+,15-,18-,19-/m0/s1/i1D3,2D3

InChI key

JJGYGPZNTOPXGV-WPGDWBRKSA-N

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General description

A stable-labeled internal standard suitable for quantitation of 6-acetylmorphine (6-MAM) levels in GC/MS or LC/MS testing for clinical toxicology, forensic analysis, urine drug testing, pain prescription monitoring and isotope dilution methods. Also known as 6-monoacetylmorphine, 6-MAM is an active metabolite of heroin and biomaker of heroin usage.

Application


  • 6-Acetylmorphine-d₆ Solution: This stable isotope-labeled compound is crucial in opioid metabolite research, providing a reliable internal standard for mass spectrometry analysis. It enhances the accuracy and precision of quantitative assessments in forensic and clinical toxicology studies (Slob et al., 2024).

  • Stable Isotope-Labeled Compounds: 6-Acetylmorphine-d₆ is utilized in pharmacokinetic studies to trace the metabolic pathways of heroin, offering insights into the bioavailability and transformation of opioids within the human body (Scherkl et al., 2024).

  • Mass Spectrometry Standards: As a mass spectrometry standard, 6-Acetylmorphine-d₆ aids in calibrating instruments and validating methodologies, ensuring robust data collection for the detection and quantification of heroin and its metabolites in biological samples (Fröhlich et al., 2024).

  • Analytical Reference Materials: This deuterated compound is a vital reference material in analytical labs, particularly for developing and testing new analytical methods in drug abuse research, forensic investigations, and therapeutic drug monitoring (Romero et al., 2024).

  • Quantitative Analysis of Heroin Metabolites: 6-Acetylmorphine-d₆ solution is essential for the quantitative analysis of heroin metabolites, providing a benchmark for measuring drug exposure levels and contributing to studies on drug addiction and its treatment (Hussein et al., 2024).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

WGK

WGK 2

Flash Point(F)

35.6 °F

Flash Point(C)

2 °C

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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