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A-013

Supelco

(±)-Amphetamine-d5 (deuterium label on side chain) solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C9D5H8N
CAS Number:
136765-27-0
Molecular Weight:
140.24
MDL number:
MFCD00673256
UNSPSC Code:
41116107
PubChem Substance ID:
329770576
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

SNAP-N-SPIKE®. SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

SMILES string

[2H]C(N)(C([2H])([2H])[2H])C([2H])C1=CC=CC=C1

InChI

1S/C9H13N/c1-8(10)7-9-5-3-2-4-6-9/h2-6,8H,7,10H2,1H3/i1D3,7D,8D

InChI key

KWTSXDURSIMDCE-ZXZAAQOOSA-N

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General description

Amphetamine, a stimulant of the phenethylamine class, is found in ADHD-treatment drugs such as Adderall®, Vyvanse®, and ProCentra®. Because of its stimulant effect, amphetamine is used recreationally as a performance-enhancer and illicit drug. This stable-labeled internal standard is suitable for quantitation of amphetamine levels in urine, serum, or plasma by LC/MS or GC/MS for urine drug testing, clinical toxicology, forensic analysis, or sports testing.

Application

  • Pharmacokinetic studies: The utilization of (±)-Amphetamine-d5 in a UPLC-MS/MS method for rapid screening of psychoactive drugs in blood exemplifies its role in pharmacokinetic analysis, aiding in the understanding of drug metabolism and clearance rates in forensic and clinical settings (Barone et al., 2023).
  • Forensic toxicology: In forensic analysis, (±)-Amphetamine-d5 serves as an internal standard for the accurate detection and quantification of amphetamines in complex biological matrices, enhancing the reliability of drug testing protocols in legal and medical investigations (Andersson et al., 2008).
  • Drug abuse monitoring: The compound′s application in the detection of amphetamine and methamphetamine in seized tablets demonstrates its critical role in public health and safety efforts, particularly in areas with high incidences of drug abuse (Alhazmi et al., 2020).

Legal Information

Adderall is a registered trademark of Richwood Pharmaceutical Company, Inc.
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
ProCentra is a registered trademark of Outlook Pharmaceuticals, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Vyvanse is a registered trademark of Shire, LLC

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Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

WGK

WGK 1

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

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Laura Nadal et al.
Molecular brain, 9(1), 67-67 (2016-06-25)
The development of the nervous system involves an initially exuberant production of neurons that make an excessive number of synaptic contacts. The initial overproduction of synapses promotes connectivity. Hebbian competition between axons with different activities (the least active are punished)

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