999974P
Avanti
16:0-18:1 Diether PE
Avanti Polar Lipids 999974P, powder
Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
1-O-hexadecanyl-2-O-(9Z-octadecenyl)-sn-glycero-3-phosphoethanolamine
Empirical Formula (Hill Notation):
C39H80 NO6 P
Recommended Products
form
powder
packaging
pkg of 1 × 10 mg (999974P-10mg)
manufacturer/tradename
Avanti Polar Lipids 999974P
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[O-]P(OCC[NH3+])(OC[C@]([H])(OCCCCCCCC/C=C\CCCCCCCC)COCCCCCCCCCCCCCCCC)=O
General description
16:0-18:1 Diether PE or 1-O-hexadecanyl-2-O-(9Z-octadecenyl)-sn-glycero-3-phosphoethanolamine is a class of glycerophospholipids that have hexadecane and octadecene chains attached to the sn-1 and sn-2 positions of the glycerol backbone respectively by ether bonds. It has ethanolamine as the alcohol moiety, attached to the phosphate group.
Biochem/physiol Actions
Certain important signaling molecules are derived from ether linked phospholipids, which act as precursors. 20 percent of the total phospholipids in human are ether linked phospholipids. Inborn errors hindering the synthesis of ether phospholipids might lead to pathological conditions. Phosphoethanolamines (PEs) serve as a substrate for several phospholipids of the cell membrane. They are associated with the phospholipid turnover. PEs are also found to prevent tumor progression.
Packaging
5 mL Clear Glass Sealed Ampule (999974P-10mg)
WGK
WGK 3
Flash Point(F)
No data available
Flash Point(C)
No data available
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Ether-linked lipids and their bioactive species
Biochemistry of Lipids, Lipoproteins and Membranes, 245-276 (2008)
Adilson Kleber Ferreira et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 67(6), 481-487 (2013-06-19)
Phosphoethanolamine (Pho-s) is a compound involved in phospholipid turnover, acting as a substrate for many phospholipids of the cell membranes. In a recent study, we showed that Pho-s has antitumor effect in the several tumor cells. In this study we
John M Dean et al.
Protein & cell, 9(2), 196-206 (2017-05-20)
Ether lipids, such as plasmalogens, are peroxisome-derived glycerophospholipids in which the hydrocarbon chain at the sn-1 position of the glycerol backbone is attached by an ether bond, as opposed to an ester bond in the more common diacyl phospholipids. This
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service