999971P
Avanti
1-C16 Ether MG
Avanti Polar Lipids 999971P, powder
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Synonym(s):
1-O-hexadecyl-sn-glycerol (HG)
Empirical Formula (Hill Notation):
C19H40O3
Recommended Products
form
powder
packaging
pkg of 1 × 250 mg (999971P-250mg)
manufacturer/tradename
Avanti Polar Lipids 999971P
lipid type
phospholipids
neutral lipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@](CO)(O)COCCCCCCCCCCCCCCCC
InChI
1S/C19H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-22-18-19(21)17-20/h19-21H,2-18H2,1H3
InChI key
OOWQBDFWEXAXPB-UHFFFAOYSA-N
General description
1-C16 Ether MG or 1-O-hexadecyl-sn-glycerol (HG) is a neutral lipid containing a saturated 16-carbon alkyl chain ether and an uncharged headgroup.
Application
1-C16 Ether MG or 1-O-hexadecyl-sn-glycerol (HG) might be used to study its effect on target gene expression in HepG2 cells. It might also be used to promote plasmalogen biosynthesis in lymphoblasts derived from Barth syndrome (BTHS) patients.
Biochem/physiol Actions
1-C16 Ether MG or 1-O-hexadecyl-sn-glycerol (HG) acts as a precursor for plasma plasmalogen (PI) biosynthesis. It is essential for maintaining the plasmalogen levels in cell lines.
Packaging
20 mL Clear Glass Screw Cap Vial (999971P-250mg)
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
新产品
Certificates of Analysis (COA)
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Santosh Phuyal et al.
The Journal of biological chemistry, 290(7), 4225-4237 (2014-12-19)
Exosomes are vesicles released by cells after fusion of multivesicular bodies with the plasma membrane. In this study, we have investigated whether ether lipids affect the release of exosomes in PC-3 cells. To increase the cellular levels of ether lipids
Extrinsic effectors regulating genes for plasmalogen biosynthetic enzymes in HepG2 cells
Maeba R, et al.
Biomedical Research and Clinical Practice, 2 (2017)
Sara L Morales-Lázaro et al.
The Journal of biological chemistry, 289(35), 24079-24090 (2014-07-19)
The transient receptor potential vanilloid 1 (TRPV1) ion channel is a polymodal protein that responds to various stimuli, including capsaicin (the pungent compound found in chili peppers), extracellular acid, and basic intracellular pH, temperatures close to 42 °C, and several
José Carlos Bozelli et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1865(6), 158677-158677 (2020-03-04)
In Barth syndrome (BTHS) mutations in tafazzin leads to changes in both the quantities and the molecular species of cardiolipin (CL), which are the hallmarks of BTHS. Contrary to the well-established alterations in CL associated with BTHS; recently a marked
Akira Abe et al.
Journal of lipid research, 48(10), 2255-2263 (2007-07-14)
A novel lysosomal phospholipase A(2) (LPLA2) with specificity toward phosphatidylethanolamine and phosphatidylcholine was previously purified and cloned. LPLA2 transfers sn-1 or sn-2 acyl groups of phospholipids to the C1 hydroxyl of the short-chain ceramide N-acetylsphingosine (NAS) under acidic conditions. The
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