900406P
Avanti
pacFA GalCer
Avanti Polar Lipids 900406P, powder
Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
D-galactosyl-β-1,1′ N-(9-(3-pent-4-ynyl-3-H-diazirin-3-yl)-nonanoyl)-D-erythro-sphingosine
Empirical Formula (Hill Notation):
C39H69N3O8
Recommended Products
form
powder
packaging
pkg of 1 × 1 mg (900406P-1mg)
pkg of 1 × 5 mg (900406P-5mg)
manufacturer/tradename
Avanti Polar Lipids 900406P
lipid type
click reagents
shipped in
dry ice
storage temp.
−20°C
SMILES string
C#CCCCC1(N=N1)CCCCCCCCC(N[C@](CO[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O2)([H])[C@H](O)/C=C/CCCCCCCCCCCCC)=O
General description
The pacFA lipid contains a photoactivable diazirine ring with a clickable alkyne group.
Biochem/physiol Actions
D-galactosyl-β-1,1′ N-(9-(3-pent-4-ynyl-3-H-diazirin-3-yl)-nonanoyl)-D-erythro-sphingosine (pacFA GalCer) may be used for a global analysis of protein-lipid interactions in living cells. pacFA acts as a precursor for the biosynthesis of bifunctional lipids. Proteins in contact with the bifunctional lipids are then cross-linked by ultraviolet (UV) irradiation of the diazirine ring. Finally, click chemistry is used to label the alkyne with a reporter molecule.
Packaging
5 mL Amber Glass Screw Cap Vial (900406P-1mg)
5 mL Amber Glass Screw Cap Vial (900406P-5mg)
WGK
WGK 3
Flash Point(F)
No data available
Flash Point(C)
No data available
Regulatory Information
新产品
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
In vivo profiling and visualization of cellular protein-lipid interactions using bifunctional fatty acids.
Per Haberkant et al.
Angewandte Chemie (International ed. in English), 52(14), 4033-4038 (2013-03-02)
Per Haberkant et al.
Biochimica et biophysica acta, 1841(8), 1022-1030 (2014-01-21)
Understanding biological processes at the mechanistic level requires a systematic charting of the physical and functional links between all cellular components. While protein-protein and protein-nucleic acid networks have been subject to many global surveys, other critical cellular components such as
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service