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900150O

Avanti

CoQ6

Avanti Polar Lipids 900150O

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Synonym(s):
Coenzyme Q6 (S. cerevisiae)
Empirical Formula (Hill Notation):
C39H58O4
CAS Number:
1065-31-2
Molecular Weight:
590.88
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 1 mg (900150O-1mg)
pkg of 1 × 5 mg (900150O-5mg)

manufacturer/tradename

Avanti Polar Lipids 900150O

lipid type

neutral glycerides
neutral lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O=C(C(OC)=C1OC)C(C)=C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)C1=O

InChI

1S/C39H58O4/c1-28(2)16-11-17-29(3)18-12-19-30(4)20-13-21-31(5)22-14-23-32(6)24-15-25-33(7)26-27-35-34(8)36(40)38(42-9)39(43-10)37(35)41/h16,18,20,22,24,26H,11-15,17,19,21,23,25,27H2,1-10H3/b29-18+,30-20+,31-22+,32-24+,33-26+

InChI key

GXNFPEOUKFOTKY-LPHQIWJTSA-N

General description

Coenzyme Q6 (CoQ6) is also known as ubiquinone-30 in Saccharomyces cerevisiae. It is a flavoprotein that utilizes flavin adenine dinucleotide (FAD) as a co-factor for the synthesis of coenzyme Q. It is composed of three conserved regions- a FAD/ nicotinamide adenine dinucleotide (NAD) + hydrogen (H) (NADH) binding motif, an adenine di phosphate (ADP) binding motif and a consensus sequence, that binds to the ribityl moiety of FAD.

Application

CoQ6 has been used:
  • as an internal standard for the liquid-chromatography mass-spectrometry for the quantification of CoQ6
  • to determine its effect on peroxisome proliferator-activated receptor (PPAR)
  • in reversed-phase high pressure liquid chromatography to quantify yeast quinones

Biochem/physiol Actions

Coenzyme Q6 (CoQ6) in the plasma membrane of Saccharomyces cerevisiae is involved in the ascorbate stabilization at the plasma membrane.

Packaging

2 mL Amber Glass Sealed Ampule (900150O-1mg)
2 mL Amber Glass Sealed Ampule (900150O-5mg)

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Idebenone and coenzyme Q10 are novel PPAR alpha gamma ligands, with potential for treatment of fatty liver diseases
Tiefenbach J, et al.
Disease models & mechanisms, 11(9) (2018)
Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylation
Spindler S R, et al.
PLoS ONE, 7(6) (2012)
CLD1 Reverses the Ubiquinone Insufficiency of Mutant cat5/coq7 in a Saccharomyces cerevisiae Model System
Kar A, et al.
PLoS ONE (2016)
CLD1 Reverses the Ubiquinone Insufficiency of Mutant cat5/coq7 in a Saccharomyces cerevisiae Model System
Kar A, et al.
Testing (2016)
Coenzyme Q biosynthesis: evidence for a substrate access channel in the FAD-dependent monooxygenase Coq6
Ismail A, et al.
PLoS Computational Biology, 12(1) (2016)
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