900130E
Avanti
13(S)HODE
Avanti Polar Lipids (900130E), ethanol solution
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Synonym(s):
13S-Hydroxy-9Z,11E-octadecanoic acid
Empirical Formula (Hill Notation):
C18H32O3
Recommended Products
Assay
99% (TLC)
form
ethanol solution
packaging
pkg of 1 × 1 mg (900130E-1mg)
pkg of 1 × 500 μg (900130E-500ug)
manufacturer/tradename
Avanti Polar Lipids (900130E)
concentration
1 mg/mL (900130E-1MG)
500 μg/mL (900130E-500UG)
lipid type
neutral glycerides
neutral lipids
shipped in
dry ice
storage temp.
−70°C
General description
13-S-hydroxyoctadecadienoic acid (13(S)HODE) is a metabolite of 15-lipoxygenase (15-LOX). It is an endogenous ligand of peroxisome proliferator-activated receptorγ (PPARγ).
Biochem/physiol Actions
13-S-hydroxyoctadecadienoic acid (13(S)HODE) inhibits cell proliferation and induces apoptosis in many human cancers. It also enhances the activity of nuclear factor κ light chain enhancer of activated B cells (NF-κB) in keratinocytes.
Packaging
2ml Amber Glass Sealed Ampule
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2
WGK
WGK 1
Flash Point(F)
55.4 °F
Flash Point(C)
13 °C
Regulatory Information
危险化学品
Certificates of Analysis (COA)
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Huiling Yuan et al.
Thorax, 65(4), 321-326 (2010-04-15)
15-S-Hydroxyeicosatetraenoic acid (15(S)-HETE) and 13-S-hydroxyoctadecadienoic acid (13(S)-HODE), both of which are metabolites of 15-lipoxygenases (15-LOXs), are endogenous ligands for peroxisome proliferator-activated receptor gamma (PPARgamma). The activation of PPARgamma inhibits cell growth and induces apoptosis in some cancers. The role of
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