900127E
Avanti
14(15) EET
Avanti Polar Lipids, ethanol solution
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Synonym(s):
(±)14(15)-epoxy-5Z,8Z,11Z-eicosatrienoic acid
Empirical Formula (Hill Notation):
C20H32O3
Recommended Products
Assay
99% (TLC)
form
ethanol solution
packaging
pkg of 1 × 500 μg (900127E-500UG)
manufacturer/tradename
Avanti Polar Lipids
concentration
500 μg/mL (900127E-500UG)
lipid type
neutral glycerides
shipped in
dry ice
storage temp.
−20°C
General description
Epoxytrienoic acid (EET) is produced from arachidonic acid. 14(15) EET is an EET, which is produced by five cytochrome P450 (CYP) epoxygenases. It is a regioisomer of EET synthesized in mammalian tissues.
Biochem/physiol Actions
Epoxytrienoic acid (EET) plays a role as lipid mediator in the renal and cardiovascular systems. 14(15) EET activates many signal transduction pathways by binding to the membrane receptors. It possesses vasoactive properties.
Packaging
2ML Amber Glass Sealed Ampule (900127E-500UG)
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2
WGK
WGK 1
Flash Point(F)
55.4 °F
Flash Point(C)
13 °C
Regulatory Information
危险化学品
Certificates of Analysis (COA)
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Cytochrome P450 epoxygenase pathway of polyunsaturated fatty acid metabolism
Spector A A and Kim H Y
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1851(4), 356-365 (2015)
Meijing Liu et al.
Antioxidants & redox signaling, 33(2), 87-116 (2020-02-11)
Aims: Acetaminophen (APAP) overdose leads to acute liver injury by inducing hepatic mitochondrial oxidative stress and inflammation. However, the
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