All Photos(1)
Synonym(s):
1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (chloride salt)
Empirical Formula (Hill Notation):
C46H89NO8PCl
Recommended Products
form
powder
packaging
pkg of 1 × 100 mg (890704P-100mg)
pkg of 2 × 100 mg (890704P-200mg)
pkg of 1 × 25 mg (890704P-25mg)
manufacturer/tradename
Avanti Polar Lipids
lipid type
cationic lipids
transfection
shipped in
dry ice
storage temp.
−20°C
SMILES string
O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)OCC.[Cl-]
General description
18:1 EPC (Cl Salt) is a cationic lipid.
Application
18:1 EPC (Cl Salt) is suitable:
- for the preparation of lipid-nanoparticles
- for the use with 90% of 1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (DOPC) to produce doped giant unilamellar vesicles
- as an emulsifier to study it′s in vitro transfection activity with respect to cationic lipid changes
Packaging
5 mL Clear Glass Sealed Ampule (890704P-100mg)
5 mL Clear Glass Sealed Ampule (890704P-200mg)
5 mL Clear Glass Sealed Ampule (890704P-25mg)
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Optimization of lipid composition in cationic emulsion as in vitro and in vivo transfection agents
Kim TW, et al.
Pharmaceutical Research, 18(1), 54-60 (2001)
Enhanced intrapulmonary delivery of anticancer siRNA for lung cancer therapy using cationic ethylphosphocholine-based nanolipoplexes
Shim G, et al.
Molecular Therapy, 21(4), 816-824 (2013)
Controlling loading and optical properties of gold nanoparticles on liposome membranes
Sau TK, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 342(1-3), 92-96 (2009)
Lipid nanoparticles for delivery of messenger RNA to the back of the eye
Patel S, et al.
J. Controlled Release, 303, 91-100 (2019)
Kabir H Biswas et al.
Langmuir : the ACS journal of surfaces and colloids, 34(4), 1775-1782 (2017-12-28)
The pathway of vesicle adsorption onto a solid support depends on the material composition of the underlying support, and there is significant interest in developing material-independent strategies to modulate the spectrum of vesicle-substrate interactions on a particular surface. Herein, using
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