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Merck
CN

890702P

Avanti

16:0 EPC (Cl Salt)

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-dipalmitoyl-sn-glycero-3-ethylphosphocholine (chloride salt)

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About This Item

Empirical Formula (Hill Notation):
C42H85NO8PCl
CAS Number:
328250-18-6
Molecular Weight:
798.55
MDL number:
MFCD07779274
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

16:0 EPC (Cl Salt), Avanti Research™ - A Croda Brand 890702P, powder

InChI

1S/C42H85NO8P.ClH/c1-7-10-12-14-16-18-20-22-24-26-28-30-32-34-41(44)47-38-40(39-50-52(46,48-9-3)49-37-36-43(4,5)6)51-42(45)35-33-31-29-27-25-23-21-19-17-15-13-11-8-2;/h40H,7-39H2,1-6H3;1H/q+1;/p-1/t40-,52?;/m1./s1

InChI key

XXTKXMLARLHZSM-WGVGMMHHSA-M

SMILES string

O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)OCC.[Cl-]

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (890702P-10mg)
pkg of 1 × 100 mg (890702P-100mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 890702P

lipid type

cationic lipids
transfection

shipped in

dry ice

storage temp.

−20°C

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Application

16:0 EPC (Cl Salt) has been used in liposome preparation. It has also been used as a component of cationic lipid mixture.

Biochem/physiol Actions

16:0 EPC has the ability to transfect DNA into cells.

General description

16:0 EPC (1,2-dipalmitoyl-sn-glycero-3-ethylphosphocholine) is a saturated phospholipid with choline as its cationic group. It exists in the gel phase at physiological temperature.

Packaging

5 mL Clear Glass Sealed Ampule (890702P-100mg)
5 mL Clear Glass Sealed Ampule (890702P-10mg)

Storage Class

11 - Combustible Solids

wgk

WGK 3

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Analysis of lipoplex structure and lipid phase changes
Liposomes, 399-423 (2010)
Biocompatible cationic lipids for the formulation of liposomal DNA vectors
Montis C, et al.
Soft Matter, 10(24), 4287-4297 (2014)
Effects of cis-and trans-unsaturated lipids on an interdigitated membrane
Smith EA, et al.
Biophysical Chemistry, 190, 1-7 (2014)
Mixtures of cationic lipid O-ethylphosphatidylcholine with membrane lipids and DNA: Phase diagrams
Koynova R and MacDonald RC
Biophysical Journal, 85(4), 2449-2465 (2003)
Chu Wang et al.
Langmuir : the ACS journal of surfaces and colloids, 36(6), 1615-1622 (2020-01-23)
Body fluids flow all over the body and affect the biological processes at biointerfaces. To simulate such a case, sum frequency generation (SFG) vibrational spectroscopy and a self-designed microfluidic chip were combined together to investigate the interaction between a pH-responsive
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