All Photos(1)
Synonym(s):
PAMPA Lipid Blend I, DOPC:Stearic Acid (80:20, w/w) in Dodecane with 1% Ethanol for use in PAMPA assay, dodecane
UNSPSC Code:
12352211
NACRES:
NA.25
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form
liquid
packaging
pkg of 1 × 3 mL (888787D-150mg)
manufacturer/tradename
Avanti Polar Lipids
concentration
50 mg/mL (888787D-150mg)
application(s)
microbiology
lipid type
phospholipids
shipped in
dry ice
storage temp.
−20°C
General description
PAMPA Lipid Blend I is a lipid solution in dodecane/ethanol. Once opened, the contents of the glass ampoule should be transferred to a glass container with PTFE-lined screw cap closure for storage at -20°C. The transfer should be performed with a glass syringe or pipette. The solution should not contact plastic, i.e., do not transfer with plastic pipette tip or store in plastic vials.
Application
The PAMPA Lipid Blend I has been used in the parallel artificial membrane permeability assay (PAMPA) for the formation of artificial membrane.
Biochem/physiol Actions
The parallel artificial membrane permeability assay (PAMPA) is useful to study the oral absorption of drugs. It helps in specifying passive transcellular diffusion.
Packaging
5 mL Clear Glass Sealed Ampule (888787D-150mg)
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Asp. Tox. 1
Supplementary Hazards
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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High-throughput artificial membrane permeability studies in early lead discovery and development
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