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880710C

Avanti

14:0 PEG1000 PE

Avanti Research™ - A Croda Brand 880710C

Synonym(s):

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] (ammonium salt)

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About This Item

CAS Number:
474922-82-2
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 2.5 mL (880710C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 880710C

concentration

10 mg/mL (880710C-25mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[NH4+]

Application

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] (14:0 PEG1000 PE) is suitable for use in lipid aggregates to characterize and study its use as a coating and a carrier in capillary electrophoresis. It might be used to prepare sterically stabilized liposome and study its characteristics by small-angle X-ray scattering (SAXS) method.

Biochem/physiol Actions

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] (14:0 PEG1000 PE) is useful in preparing polyethylene glycol (PEG)-stabilized lipid aggregates, which serve as model membranes in biotechnical and pharmaceutical applications. PEG conjugated lipids improve liposome packing in the water/hydrocarbon interface. PEGs of molecular mass less than or equal to 5000 is preferred for vesicle coating serving for efficient delivery of the drug.

Packaging

5 mL Clear Glass Sealed Ampule (880710C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Regulatory Information

危险化学品
易制毒化学品（2类）

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Maria V Lindén et al.
Electrophoresis, 29(4), 852-862 (2008-01-24)
PEG-stabilized lipid aggregates are a promising new class of model membranes in biotechnical and pharmaceutical applications. CE techniques, field-flow fractionation, light scattering, quartz crystal microbalance (QCM), and microscopic techniques were used to study aggregates composed of 1-palmitoyl-2-oleyl-sn-glycero-phosphatidylcholine (POPC) and PEG-lipid
Z Varga et al.
Chemistry and physics of lipids, 165(4), 387-392 (2012-01-10)
Synchrotron small-angle X-ray scattering analysis of the bilayer structure of a pharmacologically relevant sterically stabilized liposome system is presented. Describing the electron density profile of the bilayer with the superposition of Gaussian functions, the contribution of the poly(ethylene glycol) (PEG)

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