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Merck
CN

880420P

Avanti

18:0 PEG350 PE

Avanti Research - A Croda Brand

Synonym(s):

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] (ammonium salt)

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About This Item

CAS Number:
UNSPSC Code:
51191904
NACRES:
NA.25
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Product Name

18:0 PEG350 PE, Avanti Research - A Croda Brand 880420P, powder

InChI key

QSUSYAZEVPDIBC-KINGROEASA-N

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+]

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (880420P-25mg), pkg of 1 × 500 mg (880420P-500mg)

manufacturer/tradename

Avanti Research - A Croda Brand 880420P

shipped in

dry ice

storage temp.

−20°C

Application

18:0 PEG350 PE is suitable for liposome modification.

Packaging

30 mL Amber Wide Mouth Bottle with Screw Cap (880420P-500mg)
5 mL Clear Glass Sealed Ampule (880420P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk

WGK 3

Regulatory Information

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Zebrafish as a predictive screening model to assess macrophage clearance of liposomes in vivo
Sieber S, et al.
Nanomedicine: Nanotechnology, Biology, and Medicine, 17, 82-93 (2019)
Sandro Sieber et al.
Nanomedicine : nanotechnology, biology, and medicine, 17, 82-93 (2019-01-20)
Macrophage recognition of nanoparticles is highly influenced by particle size and surface modification. Due to the lack of appropriate in vivo screening models, it is still challenging and time-consuming to characterize and optimize nanomedicines regarding this undesired clearance mechanism. Therefore
Liming Deng et al.
Biomaterials science, 8(3), 858-870 (2019-12-07)
Hypoxic resistance, photosensitizer toxicity, and target deficiency are major challenges strongly inhibiting the efficacy of clinical photodynamic therapy (PDT) in tumor treatment. To overcome these challenges, we synthesized IR780 and catalase co-loaded liposomes to form a tumor-targeted bio-nanoreactor (LIP-IR-CAT). The

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