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880170P

Avanti

C8 PEG2000 Ceramide

Avanti Polar Lipids 880170P, powder

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Synonym(s):
N-octanoyl-sphingosine-1-{succinyl[methoxy(polyethylene glycol)2000]}
CAS Number:
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 25 mg (880170P-25mg)

manufacturer/tradename

Avanti Polar Lipids 880170P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCC)=O)COC(CCC(OOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O.C=C

General description

C8 PEG2000 Ceramide, also known as N-octanoyl-sphingosine-1-{succinyl[methoxy(polyethylene glycol)2000]}, is a polyethylene glycol (PEG)-modified lipid. Ceramide-PEGylated lipoplexes deliver siRNA to targeted sites more efficiently than 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE)-PEGylated lipoplexes.

Application

C8 PEG2000 Ceramide, or N-octanoyl-sphingosine-1-{succinyl[methoxy(polyethylene glycol)2000]} is suitable for PEGylated lipoplexes preparation.

Packaging

5 mL Amber Glass Screw Cap Vial (880170P-25mg)

WGK

WGK 3


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Anna Lechanteur et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 93, 493-503 (2016-09-07)
The delivery of small interfering RNA (siRNA) is an attractive therapeutic approach to treat several pathologies, such as viral infections or cancers. However, the stability and the efficacy of these biotherapies are still a major obstacle to their use. Cationic

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