Skip to Content
Merck
CN
All Photos(1)

Documents

880151P

Avanti

DMG-PEG 2000

Avanti Polar Lipids

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
1,2-Dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000
Empirical Formula (Hill Notation):
C122H242O50
CAS Number:
160743-62-4
Molecular Weight:
2509.20
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g
pkg of 1 × 5 g

manufacturer/tradename

Avanti Polar Lipids

application(s)

advanced drug delivery

shipped in

dry ice

storage temp.

−20°C

SMILES string

O=C(CCCCCCCCCCCCC)OCC(OC(CCCCCCCCCCCCC)=O)COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC

Looking for similar products? Visit Product Comparison Guide

General description

Dimyristoyl glycerol (DMG) molecule associates with membrane similar to phospholipids.
Structure, molecular formula and formula weight are representative of the average polymer length of the material.

Application

DMG-PEG 2000 is suitable for use in the preparation of lipid nanoparticle for microRNA and short interfering RNA delivery.

Biochem/physiol Actions

Dimyristoyl glycerol (DMG) − polyethyleneglycol (PEG) 2000 is used for liposome preparation for anticancer drug delivery studies for hepatocellular, gastrointestinal, neuroendocrine and adrenocortical carcinoma. It is also used in lipid nanoparticle preparation for siRNA (small interfering RNA) delivery.

Packaging

20 mL Clear Glass Screw Cap Vial (880151P-1G)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (880151P-5G)

also commonly purchased with this product

Product No.
Description
Pricing

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

miR-199a-3p modulates MTOR and PAK4 pathways and inhibits tumor growth in a hepatocellular carcinoma transgenic mouse model
Callegari E, et al.
Molecular Therapy. Nucleic Acids, 11(3), 485-493 (2018)
Dynamic chain conformations in dimyristoyl glycerol-dimyristoyl phosphatidylcholine mixtures. 2H-NMR studies
Schorn K and Marsh D
Biophysical Journal, 71(6), 3320-3329 (1996)
Liver-Specific silencing of Lipin1 reduces fat mass as well as hepatic triglyceride biosynthesis in mice
Kajimoto K, et al.
Biological & Pharmaceutical Bulletin, 39(10), 1653-1661 (2016)
Lipid-based drug delivery systems in cancer therapy: what is available and what is yet to come
Yingchoncharoen P, et al.
Pharmacological Reviews, 68(3), 701-787 (2016)
Advances in lipid nanoparticles for siRNA delivery
Tam Y, et al.
Pharmaceutics, 5(3), 498-507 (2013)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service