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880130C

Avanti

18:1 PEG2000 PE

Avanti Polar Lipids 880130C

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Synonym(s):
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt)
CAS Number:
474922-90-2
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 2.5 mL (880130C-25mg)
pkg of 2 × 20 mL (880130C-1g)

manufacturer/tradename

Avanti Polar Lipids 880130C

concentration

10 mg/mL (880130C-25mg)
25 mg/mL (880130C-1g)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]

Application

18:1 PEG2000 PE has been used as a component of quantum dot (QD) solution. It has also been used in fusion assay to study the inter-bilayer and bilayer-substrate interactions.

Biochem/physiol Actions

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine is a neutral lipid. It serves as a helper lipid for cationic liposomes. This product might be used for PEGylation (polyethylene glycol) of nanoparticles to increase in vivo stability. It also promotes efficient delivery.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (880130C-1g)
5 mL Clear Glass Sealed Ampule (880130C-25mg)

also commonly purchased with this product

Product No.
Description
Pricing

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Liver,Kidney, Respiratory system

WGK

WGK 3

Regulatory Information

易制毒化学品（2类）
危险化学品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Fusion of single proteoliposomes with planar, cushioned bilayers in microfluidic flow cells
Karatekin E and Rothman JE
Nature Protocols, 7, 903-903 (2012)
Carol Cho et al.
Nature communications, 10(1), 5764-5764 (2019-12-19)
The fundamental unit of chromatin, the nucleosome, is an intricate structure that requires histone chaperones for assembly. ATAD2 AAA+ ATPases are a family of histone chaperones that regulate nucleosome density and chromatin dynamics. Here, we demonstrate that the fission yeast ATAD2
Erdem Karatekin et al.
Nature protocols, 7(5), 903-920 (2012-04-21)
Many biological processes rely on membrane fusion, and therefore assays to study its mechanisms are necessary. Here we report an assay with sensitivity to single-vesicle, and even to single-molecule events using fluorescently labeled vesicle-associated v-SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein
Mudassar Mumtaz Virk et al.
Langmuir : the ACS journal of surfaces and colloids, 34(1), 395-405 (2017-12-13)
Hybrid vesicles, comprising blends of amphiphilic block copolymers and phospholipids, have attracted significant attention recently because of their unique combination of chemical and physical properties. We report a method to make unilamellar hybrid vesicles with diameters of 100 nm by
Max Piffoux et al.
ACS nano, 12(7), 6830-6842 (2018-07-06)
Extracellular vesicles (EVs) are recognized as nature's own carriers to transport macromolecules throughout the body. Hijacking this endogenous communication system represents an attractive strategy for advanced drug delivery. However, efficient and reproducible loading of EVs with therapeutic or imaging agents

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