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870852C

Avanti

C18:1(Δ9-cis) Carnitine

Avanti Research™ - A Croda Brand 870852C

Synonym(s):

oleoyl L-carnitine

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About This Item

Empirical Formula (Hill Notation):
C25H47NO4
CAS Number:
13962-05-5
Molecular Weight:
425.64
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 1 mL (870852C-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 870852C

concentration

5 mg/mL (870852C-5mg)

lipid type

bioactive lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

C[N+](C)(C)C[C@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)CC([O-])=O

InChI

1S/C25H47NO4/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-25(29)30-23(21-24(27)28)22-26(2,3)4/h12-13,23H,5-11,14-22H2,1-4H3/b13-12-

InChI key

IPOLTUVFXFHAHI-SEYXRHQNSA-N

Application

C18:1(Δ9-cis) Carnitine may be used as an internal standard in tandem mass spectrometry (MS/MS) for quantitative measurement of carnitines in plasma sample.

Biochem/physiol Actions

C18:1(Δ9-cis) Carnitine, also known as oleoyl L-carnitine, has a potential to inhibit glycine transporter 2 (GLYT2) in a non-competitive manner. It is used as an effective therapeutic for treating pain.

Packaging

5 mL Clear Glass Sealed Ampule (870852C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Regulatory Information

危险化学品
易制毒化学品（2类）

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J E Carland et al.
British journal of pharmacology, 168(4), 891-902 (2012-09-18)
Concentrations of extracellular glycine in the CNS are regulated by two Na(+)/Cl(-) -dependent glycine transporters, GlyT1 and GlyT2. Selective inhibitors of GlyT1 have been developed for the treatment of schizophrenia, whilst selective inhibitors of GlyT2 are analgesic in animal models
Lawrence C Johnson et al.
Clinical science (London, England : 1979), 132(16), 1765-1777 (2018-06-20)
Advancing age is associated with impairments in numerous physiological systems, leading to an increased risk of chronic disease and disability, and reduced healthspan (the period of high functioning healthy life). The plasma metabolome is thought to reflect changes in the

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