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870704P

Avanti

04:0 Coenzyme A

Avanti Polar Lipids

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Synonym(s):
butanoyl Coenzyme A (sodium salt)
Empirical Formula (Hill Notation):
C25H39N7Na3O17P3S
CAS Number:
799812-79-6
Molecular Weight:
903.57
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 5 mg (870704P-5mg)

manufacturer/tradename

Avanti Polar Lipids

application(s)

lipidomics

lipid type

coenzymes

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@@](C(NCCC(NCCSC(CCC)=O)=O)=O)(C(C)(COP([O-])(OP([O-])(OC[C@H]([C@H]1OP([O-])(O)=O)O[C@H]([C@@H]1O)N2C3=C(C(N)=NC=N3)N=C2)=O)=O)C)[H].[Na+].[Na+].[Na+]

InChI

1S/C25H42N7O17P3S.3Na/c1-4-5-16(34)53-9-8-27-15(33)6-7-28-23(37)20(36)25(2,3)11-46-52(43,44)49-51(41,42)45-10-14-19(48-50(38,39)40)18(35)24(47-14)32-13-31-17-21(26)29-12-30-22(17)32;;;/h12-14,18-20,24,35-36H,4-11H2,1-3H3,(H,27,33)(H,28,37)(H,41,42)(H,43,44)(H2,26,29,30)(H2,38,39,40);;;/q;3*+1/p-3/t14-,18?,19+,20+,24-;;;/m1.../s1

InChI key

PRMIKLPNYYDDCC-XRHOYZRHSA-K

General description

04:0 Coenzyme A, also known as butanoyl coenzyme A, is a coenzyme A derivative of butanoic acid. 04:0 Coenzyme A is a short-chain acyl CoA and is an intermediate of fatty acid degradation.

Biochem/physiol Actions

04:0 Coenzyme A acts as a source of N-acyl chain in the synthesis of N-butanoyl-L-homoserine lactone (BHL) by LuxI homologue RhlI (VsmI). Butanoyl coenzyme A serves as an intermediate in the synthesis of butyrate, which is involved in maintaining colonic homeostasis and gut health. It also has an ability to inhibit citrate synthase (CS). 

Packaging

5 mL Amber Glass Screw Cap Vial (870704P-5mg)

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Julian Trachsel et al.
Applied and environmental microbiology, 82(22), 6788-6798 (2016-10-30)
Studying the host-associated butyrate-producing bacterial community is important, because butyrate is essential for colonic homeostasis and gut health. Previous research has identified the butyryl coenzyme A (CoA):acetate-CoA transferase (EC 2.3.8.3) as a gene of primary importance for butyrate production in
Y Jiang et al.
Molecular microbiology, 28(1), 193-203 (1998-05-21)
In Pseudomonas aeruginosa, synthesis of the quorum-sensing signal molecules N-butanoyl-L-homoserine lactone (BHL) and N-hexanoyl-L-homoserine lactone (HHL) requires the Luxl homologue Rhll(Vsml). By using thin-layer chromatography in conjunction with high-performance liquid chromatography (HPLC) and mass spectrometry, we show that purified Rhll
J C Lai et al.
Research communications in chemical pathology and pharmacology, 82(3), 331-338 (1993-12-01)
We investigated the hypothesis that one mechanism underlying fatty acid toxicity is the selective inhibition of rate-limiting and/or regulated tricarboxylic acid cycle and related enzymes by fatty acyl coenzyme A (CoA) derivatives by examining the effects of several fatty acyl

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