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870605P

Avanti

16:0-09:0 (ALDO) PC

Avanti Polar Lipids 870605P, powder

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Synonym(s):
1-palmitoyl-2-(9′-oxo-nonanoyl)-sn-glycero-3-phosphocholine
Empirical Formula (Hill Notation):
C33H64NO9P
CAS Number:
Molecular Weight:
649.84
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 1 mg (870605P-1mg)

manufacturer/tradename

Avanti Polar Lipids 870605P

lipid type

phospholipids
phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCC([H])=O)=O)COC(CCCCCCCCCCCCCCC)=O)=O

General description

16:0-09:0 (ALDO) PC is an oxidized lipid.

Application

16:0-09:0 (ALDO) PC has been used to selectively induce prostaglandin E2 in human broncho epithelial cell line.

Packaging

5 mL Clear Glass Sealed Ampule (870605P-1mg)

also commonly purchased with this product

WGK

WGK 3

Flash Point(F)

No data available

Flash Point(C)

No data available


Certificates of Analysis (COA)

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Shannon R Murphy et al.
American journal of respiratory cell and molecular biology, 47(6), 815-823 (2012-09-11)
Postnatally, the lung continues to grow and differentiate while interacting with the environment. Exposure to ozone (O(3)) and allergens during postnatal lung development alters structural elements of conducting airways, including innervation and neurokinin abundance. These changes have been linked with
Postnatal exposure history and airways: oxidant stress responses in airway explants
Murphy SR, et al.
American Journal of Respiratory Cell and Molecular Biology, 47(6), 815-823 (2012)
Luma da Costa Loureiro et al.
Molecular immunology, 122, 163-172 (2020-05-04)
Pulmonary surfactant plays an important role in lung surface tension, defense against invading pathogens, and immune response. Furthermore, alveolar macrophages (AM) that comprise the front line of immune defense against inhaled microorganisms are covered by a layer of pulmonary fluid.
Morten Dahl et al.
The Journal of clinical investigation, 117(3), 757-764 (2007-03-03)
Alveolar macrophages (AMs) express the class A scavenger receptors (SRAs) macrophage receptor with collagenous structure (MARCO) and scavenger receptor AI/II (SRA-I/II), which recognize oxidized lipids and provide innate defense against inhaled pathogens and particles. Increased MARCO expression in lungs of
Agnieszka Olżyńska et al.
Langmuir : the ACS journal of surfaces and colloids, 36(4), 1023-1033 (2020-01-07)
We introduce and study a multicomponent lipid film mimicking lipid composition of the human lung surfactant. It consists of phospholipids with various lipid headgroups and tail saturation. Furthermore, it includes cholesterol and oxidized lipids. Langmuir trough and fluorescence microscopy experiments

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