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Merck
CN

870282C

Avanti

18:1 Biotinyl PE

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(biotinyl) (sodium salt)

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About This Item

Empirical Formula (Hill Notation):
C51H91N3O10PNaS
CAS Number:
384835-53-4
Molecular Weight:
992.31
MDL number:
MFCD22495348
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

18:1 Biotinyl PE, Avanti Research™ - A Croda Brand 870282C

SMILES string

[H][C@@](COP([O-])(OCCN([H])C(CCCC[C@](SC[C@@]1(NC(N2)=O)[H])([C@]12[H])[H])=O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]

InChI

1S/C51H92N3O10PS.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-37-48(56)61-41-44(64-49(57)38-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)42-63-65(59,60)62-40-39-52-47(55)36-34-33-35-46-50-45(43-66-46)53-51(58)54-50;/h17-20,44-46,50H,3-16,21-43H2,1-2H3,(H,52,55)(H,59,60)(H2,53,54,58);/q;+1/p-1/b19-17-,20-18-;/t44-,45+,46+,50+;/m1./s1

InChI key

ZGFSYDGJPSEMJM-AOAFAMOJSA-M

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (870282C-25mg)
pkg of 1 × 4 mL (870282C-100mg)
pkg of 2 × 4 mL (870282C-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 870282C

concentration

10 mg/mL (870282C-25mg)
25 mg/mL (870282C-100mg)
25 mg/mL (870282C-200mg)

shipped in

dry ice

storage temp.

−20°C

Application

18:1 Biotinyl PE is suitable: to tag N-glycolyl-monosialodihexosyl-ganglioside (NGcGM3) in the competitive assay, in preparation of small unilamellar vesicle, to test the functionalization of Polydimethylsiloxane (PDMS) polymer.

General description

18:1 Biotinyl PE, also referred as 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(biotinyl), belongs to a class of head group modified functionalized lipids.

Packaging

5 mL Clear Glass Sealed Ampule (870282C-100mg)
5 mL Clear Glass Sealed Ampule (870282C-200mg)
5 mL Clear Glass Sealed Ampule (870282C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

Regulatory Information

易制毒化学品（2类）
危险化学品
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Bo Huang et al.
Lab on a chip, 6(3), 369-373 (2006-03-03)
Polydimethylsiloxane (PDMS) surfaces can be functionalized with biotin groups by adding biotinylated phospholipids to the PDMS prepolymer before curing. The addition of beta-D-dodecyl-N-maltoside (DDM) in the solution blocks non-specific protein binding on these functionalized PDMS surfaces. We characterize the surface
H Zhan
Journal of biochemical and biophysical methods, 41(1), 13-19 (1999-10-08)
A general method for measuring interaction of liposome-protein (or potentially small molecules) was developed. This method utilizes biotinylated liposomes to incubate with interactants. Streptavidin-coated paramagnetic resins were then added and the liposomes (along with bound materials) can be quickly separated
M Virginia Gentilini et al.
Cancer immunology, immunotherapy : CII, 65(5), 551-562 (2016-03-13)
The expression of N-glycolyl-monosialodihexosyl-ganglioside (NGcGM3) in humans is restricted to cancer cells; therefore, it is a tumor antigen. There are measurable quantities of circulating anti-NGcGM3 antibodies (aNGcGM3 Abs) in human serum. Interestingly, some people have circulating Ag-specific immunoglobulins G (IgGs)
Ingrid Albertsson et al.
Scientific reports, 9(1), 17234-17234 (2019-11-23)
Denitrification is a microbial pathway that constitutes an important part of the nitrogen cycle on earth. Denitrifying organisms use nitrate as a terminal electron acceptor and reduce it stepwise to nitrogen gas, a process that produces the toxic nitric oxide
Zachary I Imam et al.
Langmuir : the ACS journal of surfaces and colloids, 35(49), 16281-16289 (2019-11-16)
Cytoskeletal filaments and motor proteins are critical components in the transport and reorganization of membrane-based organelles in eukaryotic cells. Previous studies have recapitulated the microtubule-kinesin transport system in vitro to dynamically assemble large-scale nanotube networks from multilamellar liposomes and polymersomes.
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