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870222P

Avanti

18:1 Succinyl PE

Avanti Polar Lipids 870222P, powder

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Synonym(s):
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl) (sodium salt)
Empirical Formula (Hill Notation):
C45H81NO11PNa
CAS Number:
111613-33-3
Molecular Weight:
866.09
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 2 × 100 mg (870222P-200mg)
pkg of 1 × 25 mg (870222P-25mg)

manufacturer/tradename

Avanti Polar Lipids 870222P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCN([H])C(CCC(O)=O)=O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]

InChI

1S/C45H82NO11P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-44(50)54-39-41(40-56-58(52,53)55-38-37-46-42(47)35-36-43(48)49)57-45(51)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,41H,3-16,21-40H2,1-2H3,(H,46,47)(H,48,49)(H,52,53);/q;+1/p-1/b19-17-,20-18-;/t41-;/m1./s1

InChI key

KKEGOYIHHIJUOK-NFCDTPQPSA-M

General description

18:1 Succinyl PE , also known as 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl) (N-succinyl DPPE), is a head group modified functionalized lipid. Functionalized lipids perform the role of reporter molecules. N-succinyl DPPE in combination with poly(vinyl pyrrolidone) is used in preparation of new drug delivery systems.

Packaging

5 mL Clear Glass Sealed Ampule (870222P-200mg)
5 mL Clear Glass Sealed Ampule (870222P-25mg)

WGK

WGK 3

Regulatory Information

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Poly (vinyl pyrrolidone) conjugated lipid system for the hydrophobic drug delivery
Lee HY, et al.
Macromolecular Research, 15(6), 547-552 (2007)
Mariusz Kepczynski et al.
Biochimica et biophysica acta, 1858(10), 2362-2379 (2016-03-08)
Synthetic lipids and surfactants that do not exist in biological systems have been used for the last few decades in both basic and applied science. The most notable applications for synthetic lipids and surfactants are drug delivery, gene transfection, as

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