860837P
Avanti
CER7-2′R,6R(d9)
Avanti Polar Lipids 860837P, powder
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Synonym(s):
N(2′-(R)-hydroxypalmitoyl(d9)) 6R-hydroxysphingosine
Empirical Formula (Hill Notation):
C34H58D9NO5
Recommended Products
form
powder
packaging
pkg of 1 × 1 mg (860837P-1mg)
manufacturer/tradename
Avanti Polar Lipids 860837P
shipped in
dry ice
storage temp.
−20°C
SMILES string
CCCCCCCCCCCC[C@@H](O)/C=C/[C@@H](O)[C@@H](NC([C@H](O)CCCCCCCCCCC([2H])(C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])[2H])=O)CO
General description
6-Hydroxysphingosine is one of the moieties that make up the class of ceramides, which are lipids localized to stratum corneum. It is formed due to incorporation of hydroxyl group to long chain bases.
Application
N(2′-(R)-hydroxypalmitoyl(d9)) 6R-hydroxysphingosine (CER7-2′R,6R(d9)) has been used as an internal standard for qualitative analysis of stratum corneum (SC) ceramides in humans and mice by liquid chromatography–mass spectrometry (LC-MS)/MS.
Biochem/physiol Actions
6-Hydroxysphingosine is one of the sphingoid bases in skin.
Packaging
5 mL Amber Glass Screw Cap Vial (860837P-1mg)
WGK
WGK 3
Flash Point(F)
No data available
Flash Point(C)
No data available
Regulatory Information
美国出口管控1C298产品
Certificates of Analysis (COA)
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Find documentation for the products that you have recently purchased in the Document Library.
Principles and Practice of Skin Toxicology, 21-21 (2008)
Identification of lipids of the stratum corneum by high performance thin layer chromatography and mass spectrometry
Jamin EL, et al.
Eur. J. Mass Spectrom., 2018, 1469066718815380-1469066718815380 (2018)
Lipids and the Permeability and Antimicrobial Barriers of the Skin
Wertz Philip W
Journal of Lipids, 2018 (2018)
Momoko Kawana et al.
Journal of lipid research, 61(6), 884-895 (2020-04-09)
Ceramides are the predominant lipids in the stratum corneum (SC) and are crucial components for normal skin barrier function. Although the composition of various ceramide classes in the human SC has been reported, that in mice is still unknown, despite
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