860833P
Avanti
C6(6-azido) GalCer
Avanti Polar Lipids 860833P, powder
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Synonym(s):
D-galactosyl-β-1,1′ N-(6"-azidohexanoyl)-D-erythro-sphingosine
Empirical Formula (Hill Notation):
C30H56 N4O8
Recommended Products
form
powder
packaging
pkg of 1 × 5 mg (860833P-5mg)
manufacturer/tradename
Avanti Polar Lipids 860833P
lipid type
click reagents
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCN=[N+]=[N-])=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@H]([C@H]1CO)O
General description
C6(6-azido) GalCer, also known as D-galactosyl-β-1,1′ N-(6"-azidohexanoyl)-D-erythro-sphingosine is a head group modified lipid comprising an omega-terminal azide. The terminal azide group is involved in a highly specific linking reaction with alkyne-containing reagents, known as ‘click chemistry′, in the presence of a copper (Cu)-containing catalyst. Copper-catalyzed azide−alkyne click chemistry plays a vital role in bioconjugation.
Packaging
5 mL Amber Glass Screw Cap Vial (860833P-5mg)
Flash Point(F)
No data available
Flash Point(C)
No data available
Regulatory Information
监管及禁止进口产品
Certificates of Analysis (COA)
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Stanislav I Presolski et al.
Current protocols in chemical biology, 3(4), 153-162 (2011-01-01)
The copper-catalyzed azide-alkyne cycloaddition reaction is widely used for the connection of molecular entities of all sizes. A protocol is provided here for the process with biomolecules. Ascorbate is used as reducing agent to maintain the required cuprous oxidation state.
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