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860685P

Avanti

Lyso-SM-d9

powder, Avanti Polar Lipids (860685P)

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Synonym(s):
Sphingosylphosphorylcholine-d9
Empirical Formula (Hill Notation):
C23H40D9N2O5P
CAS Number:
2315262-28-1
Molecular Weight:
473.67
UNSPSC Code:
12352211
NACRES:
NA.12

Assay

99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (860685P-1MG)

manufacturer/tradename

Avanti Polar Lipids (860685P)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(N)COP([O-])(OCC[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O

General description

Lyso-SM-d9 is a deuterated lyso-SM. Lyso sphingomyelin (Lyso-SM) is obtained from sphingomyelin due to the cleavage of N-acyl linkage of ceramides in sphingomyelin by the help of hydrolase.

Biochem/physiol Actions

Lyso sphingomyelin (Lyso-SM) functions as lipid mediators. It plays a vital role in cellular functioning of the skin, blood vessels, brain and heart. It also helps in the functioning of the immune system.

Packaging

5 mL Amber Glass Screw Cap Vial

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A novel enzyme that cleaves the N-acyl linkage of ceramides in various glycosphingolipids as well as sphingomyelin to produce their lyso forms.
Ito M
The Journal of Biological Chemistry, 270(41), 24370-24374 (1995)
Lyso-sphingomyelin is elevated in dried blood spots of Niemann-Pick B patients
Chuang W L, et al.
Molecular Genetics and Metabolism, 111(2), 209-211 (2014)

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