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860670P

Avanti

Sphingosine (d14:1)

Avanti Research - A Croda Brand 860670P, powder

Synonym(s):

D-erythro-Sphingosine (C14 Base)

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About This Item

Empirical Formula (Hill Notation):
C14H29NO2
CAS Number:
Molecular Weight:
243.39
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 5 mg (860670P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 860670P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC[C@@](N)([H])[C@]([H])(O)/C=C/CCCCCCCCC

General description

Sphingosine (d14:1), also referred as tetradecasphing-4-enine, is a C14 analog of sphingosine. It is a major part of sphingoid bases in Musca domestica larvae and adults.

Biochem/physiol Actions

Sphingosine acts as a negative regulator of cell proliferation. It induces apoptosis. It modulates the activities of enzymes such as, phospholipases and protein kinases. In addition, sphingosine also regulate ion channels, cannabinoid receptor type 1 (CB-1) receptors and steroidogenic factor 1 (SF-1) receptors.

Packaging

5 mL Amber Glass Screw Cap Vial (860670P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

No data available

Flash Point(C)

No data available


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lipid Mediators and Their Metabolism in the Brain (2011)
Olivier Cuvillier
Biochimica et biophysica acta, 1585(2-3), 153-162 (2003-01-18)
The sphingolipid metabolites ceramide, sphingosine, and sphingosine 1-phosphate contribute to controlling cell proliferation and apoptosis. Ceramide and its catabolite sphingosine act as negative regulators of cell proliferation and promote apoptosis. Conversely, sphingosine 1-phosphate, formed by phosphorylation of sphingosine by a
The occurrence of tetradecasphing-4-enine and hexadecasphing-4-enine as the principal sphingosines of Musca domestica larvae and adults.
L L Bieber et al.
Biochimica et biophysica acta, 187(1), 157-159 (1969-07-29)

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