860649P
Avanti
C24 Ceramide (d17:1/24:0)
Avanti Research™ - A Croda Brand 860649P, powder
Synonym(s):
N-lignoceroyl-D-erythro-sphingosine (C17 base)
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All Photos(2)
About This Item
Empirical Formula (Hill Notation):
C41H81NO3
CAS Number:
Molecular Weight:
636.09
UNSPSC Code:
12352211
NACRES:
NA.25
form
powder
packaging
pkg of 1 × 10 mg (860649P-10mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860649P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@]([H])(NC(CCCCCCCCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCC
General description
C24 Ceramide (d17:1/24:0) is a synthetic ceramide derived from a C17 sphingosine with lignoceric acid. Ceramide synthase 2 is responsible for the synthesis of C24 ceramide.
Application
C24 Ceramide (d17:1/24:0) has been used as an internal standard to quantify ceramide content in both subcutaneous and visceral adipose tissue by ultraperformance liquid chromatography - tandem mass spectrometery (UPLC-MS/MS).
Biochem/physiol Actions
C24 Ceramide (d17:1/24:0) plays a vital role in inducing cell death. Altered levels of C24 Ceramide might be a potential indication in tumor monitoring.
Packaging
5 mL Amber Glass Screw Cap Vial (860649P-10mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Agnieszka U Blachnio-Zabielska et al.
International journal of molecular sciences, 19(12) (2018-12-14)
Ceramide accumulation in muscle and in liver is implicated in the induction of insulin resistance. Much less in known about the role of ceramide in adipose tissue. The aim of the present study was to elucidate the role of ceramide
Luisa Coderch et al.
American journal of clinical dermatology, 4(2), 107-129 (2003-01-30)
Ceramides are the major lipid constituent of lamellar sheets present in the intercellular spaces of the stratum corneum. These lamellar sheets are thought to provide the barrier property of the epidermis. It is generally accepted that the intercellular lipid domain
Ling Chen et al.
Oncology reports, 34(1), 447-454 (2015-05-16)
Endocannabinoids and ceramides have demonstrated growth inhibition, cell death induction and pro-apoptotic activity in cancer research. In the present study, we describe the profiles of two major endocannabinoids, ceramides, free fatty acids and relevant metabolic enzymes in 47 pairs of
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