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860552P

Avanti

Biotin S1P

Avanti Polar Lipids 860552P, powder

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Synonym(s):
omega-biotinyl D-erythro-sphingosine-1-phosphate
Empirical Formula (Hill Notation):
C28H53N4O7PS
CAS Number:
799812-63-8
Molecular Weight:
620.78
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (860552P-100ug))

manufacturer/tradename

Avanti Polar Lipids 860552P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@]1(CCCCC(NCCCCCCCCCCCCC/C=C/[C@@]([H])(O)[C@]([NH3+])([H])COP([O-])(O)=O)=O)SC[C@@]2([H])[C@]1([H])NC(N2)=O

InChI

1S/C28H53N4O7PS/c29-22(20-39-40(36,37)38)24(33)16-12-10-8-6-4-2-1-3-5-7-9-11-15-19-30-26(34)18-14-13-17-25-27-23(21-41-25)31-28(35)32-27/h12,16,22-25,27,33H,1-11,13-15,17-21,29H2,(H,30,34)(H2,31,32,35)(H2,36,37,38)/b16-12+/t22-,23-,24+,25-,27-/m0/s1

InChI key

JHROEHVYJZWKKP-RPRIXWAOSA-N

General description

Biotinylated sphingosine 1-phosphate (Biotin S1P) is produced by the phosphorylation of biotinyl sphingosine by recombinant human sphingosine kinase 1 and 2 (hSK1 and hSK2). Biotinyl sphingosine is derived from sphingosine and it contains a biotin unit at the ω-terminal of its fatty-acid chain.

Application

Biotinylated sphingosine 1-phosphate (Biotin S1P) is suitable to be used as an antigen to preabsorb murine monoclonal antibody, LT1002.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (860552P-100ug)

WGK

WGK 3

Certificates of Analysis (COA)

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An assay for sphingosine kinase activity using biotinylated sphingosine and streptavidin-coated membranes
Roberts J, et al.
Analytical biochemistry, 331(1), 122-129 (2004)
Immunohistochemical detection of sphingosine-1-phosphate and sphingosine kinase-1 in human tissue samples
Sphingosine-1-Phosphate, 55-67 (2012)

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