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860373P

Avanti

18:0 PE-d70

Avanti Polar Lipids 860373P, powder

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Synonym(s):
1,2-distearoyl-d70-sn-glycero-3-phosphoethanolamine
Empirical Formula (Hill Notation):
C41H12NO8PD70
CAS Number:
326495-43-6
Molecular Weight:
818.50
UNSPSC Code:
12352100
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (860373P-10mg)

manufacturer/tradename

Avanti Polar Lipids 860373P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H

General description

1,2-distearoyl-d70-sn-glycero-3-phosphoethanolamine (18:0 PE-d70) is a deuterated phosphoethanolamine (PE) in which 70 protons of distearoyl are replaced.
Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.

Application

1,2-distearoyl-d70-sn-glycero-3-phosphoethanolamine (18:0 PE-d70) has been used in the preparation of 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE) bilayers to determine the pressure dependence of DSPE flip-flop.

Packaging

5 mL Amber Glass Screw Cap Vial (860373P-10mg)

WGK

WGK 3

Regulatory Information

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Timothy C Anglin et al.
Biochemistry, 48(43), 10220-10234 (2009-09-15)
In order to better characterize the dependence of lipid flip-flop rate and thermodynamics on the nature of the lipid headgroup, we have studied the kinetics of flip-flop for single-lipid and mixed-lipid bilayers consisting of 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) and 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE) as

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