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860372P

Avanti

16:0 PE-d62

Avanti Polar Lipids 860372P, powder

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Synonym(s):
1,2-dipalmitoyl-d62-sn-glycero-3-phosphoethanolamine
Empirical Formula (Hill Notation):
C37H12NO8PD62
CAS Number:
326495-42-5
Molecular Weight:
754.34
UNSPSC Code:
12352100
NACRES:
NA.12

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (860372P-10mg)

manufacturer/tradename

Avanti Polar Lipids 860372P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)COC(C([2H])([2H]

General description

1,2-dipalmitoyl-d62-sn-glycero-3-phosphoethanolamine (16:0 PE-d62) is a deuterated phosphoethanolamine (PE) in which 62 protons of dipalmitoyl are replaced.
Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.

Application

1,2-dipalmitoyl-d62-sn-glycero-3-phosphoethanolamine (16:0 PE-d62) has been used as an apolar lipid internal standard for mass spectrometry. It may be used in the preparation of levuglandin hydroxylactam.

Packaging

5 mL Amber Glass Screw Cap Vial (860372P-10mg)

WGK

WGK 3

Regulatory Information

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Wei Li et al.
Free radical biology & medicine, 47(11), 1539-1552 (2009-09-16)
Levuglandins (LGs) and isolevuglandins (isoLGs, also called "isoketals" or "isoKs") are extraordinarily reactive products of cyclooxygenase- and free radical-induced oxidation of arachidonates. We now report the detection in vivo and quantitative analysis of LG/isoLG adducts that incorporate the amino group
Xiyuan Lu et al.
Scientific reports, 7(1), 3455-3455 (2017-06-16)
To maintain core body temperature in cold conditions, mammals activate a complex multi-organ metabolic response for heat production. White adipose tissue (WAT) primarily functions as an energy reservoir, while brown adipose tissue (BAT) is activated during cold exposure to generate

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