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860353P

Avanti

16:0 PC-d13

Avanti Polar Lipids 860353P, powder

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Synonym(s):
1,2-dipalmitoyl-sn-glycero-3-phosphocholine-1,1,2,2-d4-N,N,N-trimethyl-d9
Empirical Formula (Hill Notation):
C40H67NO8PD13
CAS Number:
86531-55-7
Molecular Weight:
747.12
UNSPSC Code:
12352100
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (860353P-10mg)

manufacturer/tradename

Avanti Polar Lipids 860353P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OC([2H])([2H])C([2H])([2H])[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O

General description

16:0 PC-d13 is a deuterated phosphocholine (PC) in which 13 protons of dipalmitoyl are replaced by deuterium.

Application

16:0 PC-d13 has been used in the preparation of asymmetric large unilamellar vesicles (aLUVs) to measure lipid translocation.

Packaging

5 mL Amber Glass Screw Cap Vial (860353P-10mg)

WGK

WGK 3

Regulatory Information

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1H NMR shows slow phospholipid flip-flop in gel and fluid bilayers
Marquardt D, et al.
Langmuir, 33(15) (2017)
Drew Marquardt et al.
Langmuir : the ACS journal of surfaces and colloids, 33(15), 3731-3741 (2017-01-21)
We measured the transbilayer diffusion of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) in large unilamellar vesicles, in both the gel (Lβ') and fluid (Lα) phases. The choline resonance of headgroup-protiated DPPC exchanged into the outer leaflet of headgroup-deuterated DPPC-d13 vesicles was monitored using 1H

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Critical Micelle Concentrations (CMCs) - Avanti® Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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