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860347P

Avanti

14:0 PC-d63

Avanti Research™ - A Croda Brand, powder

Synonym(s):

1,2-Dimyristoyl-d54-sn-glycero-3-phosphocholine-N,N,N-trimethyl-d9

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About This Item

Empirical Formula (Hill Notation):
C36H9NO8PD63
CAS Number:
326495-30-1
Molecular Weight:
741.32
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (860347P-10MG)

manufacturer/tradename

Avanti Research™ - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)(OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2

General description

Phosphatidylcholine (PC) (Lecithins) has two fatty acid chains attached to a head group. Generally, PC has saturated fatty acid in the sn-1 position and unsaturated fatty acid in the sn-2 position. It has a quaternary ammonium group and a phosphate moiety in the head group, existing as a zwitterion in a wide range of pH. The fatty acid in PC is mostly palmitic, stearic, oleic, linolenic and arachidonic acid. It is present abundantly in the mammalian membranes. PC is principally synthesized from cytidine diphosphate-choline (CDP-choline). Selective deuteration of this lipid may be used in the structural studies using techniques such as nuclear magnetic resonance (NMR), neutron reflectivity and small-angle neutron scattering.

Biochem/physiol Actions

Phosphatidylcholine (PC) is essential for cholesterol trafficking and membrane cholesterol homeostasis. It acts as the precursor for the synthesis of sphingomyelin. PC plays a key role in the synthesis of second messenger and signaling molecules like diacyl glycerol, lysophosphatidic acid, phosphatidic acid and arachidonic acid.

Packaging

5 mL Amber Glass Screw Cap Vial (860347P-10MG)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

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Essentials of Medical Biochemistry (2011)
The Membranes of Cells (2016)
Phosphatidylcholine: greasing the cholesterol transport machinery
Lagace TA
Lipid insights, 8, LPI-S31746 (2015)
Biosynthetic preparation of selectively deuterated phosphatidylcholine in genetically modified Escherichia coli
Maric S, et al.
Applied Microbiology and Biotechnology, 99(1), 241-254 (2015)
The Kennedy pathway?de novo synthesis of phosphatidylethanolamine and phosphatidylcholine
Gibellini F and Smith TK
IUBMB Life, 62(6), 414-428 (2010)

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