855779P
Avanti
22:0 Lyso PC
1-behenoyl-2-hydroxy-sn-glycero-3-phosphocholine, powder
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Synonym(s):
1-docosanoyl-sn-glycero-3-phosphocholine; PC(22:0/0:0)
Empirical Formula (Hill Notation):
C30H62NO7P
Recommended Products
Assay
>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)
form
powder
packaging
pkg of 1 × 25 mg (855779P-25mg)
manufacturer/tradename
Avanti Polar Lipids 855779P
shipped in
dry ice
storage temp.
−20°C
SMILES string
O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCCCCCCCCCCCC)=O
Application
22:0 Lyso PC may be used as a standard to screen X-linked adrenoleukodystrophy (X-ALD) in newborns using positive ion electrospray (ESI) combined liquid chromatography-tandem spectrometric (LC-MS/MS) technique.
Packaging
5 mL Amber Glass Screw Cap Vial (855779P-25mg)
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Description
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Newborn screening for X-linked adrenoleukodystrophy (X-ALD): validation of a combined liquid chromatography-tandem mass spectrometric (LC-MS/MS) method
Hubbard WC, et al.
Molecular Genetics and Metabolism, 97(3), 212-220 (2009)
Walter C Hubbard et al.
Molecular genetics and metabolism, 89(1-2), 185-187 (2006-07-11)
Utilizing combined liquid chromatography-tandem mass spectrometry (LC-MS/MS) as the analytical method, we have demonstrated a ten to sixtyfold excess of lysophosphatidyl choline containing hexacosanoic acid (26:0) in dried blood spots on a filter paper matrix from 25 male patients with
Francesca Saitta et al.
Colloids and surfaces. B, Biointerfaces, 186, 110715-110715 (2019-12-17)
A fifteen-components model membrane that reflected the 80 % of phospholipids present in Insulin Secretory Granules was obtained and thermodynamic exploitation was performed, through micro-DSC, in order to assess the synergic contributions to the stability of a mixed complex system
Kelsey B Law et al.
Autophagy, 13(5), 868-884 (2017-05-20)
Peroxisome biogenesis disorders (PBDs) are metabolic disorders caused by the loss of peroxisomes. The majority of PBDs result from mutation in one of 3 genes that encode for the peroxisomal AAA ATPase complex (AAA-complex) required for cycling PEX5 for peroxisomal
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